checkNo.replicates(clippda)
checkNo.replicates()所属R语言包：clippda
A function to detect disparity in the number of replicates across assays
一个函数来检测数量悬殊复制整个检测
译者：生物统计家园网 机器人LoveR
描述----------Description----------
Sometimes in a mass spectrometry experiment, it happens that a few samples have been mislabelled. Mislabelling means that some replicates are in the wrong sample group, and this results in some samples having more (or less) replicates than the number intended by the experimentalist. Apart from disparity in the number of replicates due to mislabelling, a few samples, e.g. the quality control (QC) samples, are often assayed several times. The aim is to analyze data with the same number of technical replicates (in this case, duplicates) for every sample. The function checkNo.replicates identifies samples with a disparate number of replicates. The identified samples are treated as follows:
有时在质谱实验，它发生的几件样品已经被贴错标签。误报是指，有些重复是错误的样本组中，有更多（或更少）在一些样品结果重复的数量比实验者打算。除了数量悬殊复制误报，几样，如因质量控制（QC）样品，往往检测几次。其目的是分析数据与相同数量的复制技术为每一个样本（在这种情况下，重复）。功能checkNo.replicates标识与复制不同数量的样本。确定的样品被视为如下：
(i) The QC samples can be independently analysed to ascertain the reproducibility of the data.
（一）QC样品可以独立进行分析，以确定数据的重复性。
(ii) The samples with no replicates are discarded from further analysis.
（二）不重复的样品被丢弃从进一步的分析。
(iii) The samples with more replicates than expected, due to mislabelling (or otherwise), are pre-processed using the function: mostSimilarTwo which detects and discards replicates which give conflicting peak information compared to the rest of the replicates. Here, the two most similar replicates are treated as the correct replicates for the sample in question.
（三）有更多的样本复制低于预期，由于误报（或其他），预先处理使用功能：mostSimilarTwo检测和丢弃重复给冲突的高峰相比，其余的复制信息。在这里，两个最相似的复制是正确的复制样品中的问题来处理。
用法----------Usage----------
checkNo.replicates(rawData, no.peaks, no.replicates)
参数----------Arguments----------
参数：rawData
Duplicate data in the same format as the raw data from the Biomarker wizard software.
Biomarker Wizard软件的原始数据，在相同的格式复制数据。
参数：no.peaks
The number of peaks detected by the Biomarker wizard
峰检测的生物标志物向导
参数：no.replicates
The number of replicates intended by the biologist.
拟由生物学家的重复次数。
值----------Value----------
It returns a vector whose elements are labels for samples with a disparate number peaks.
它返回一个向量，其元素是用不同的数峰样品的标签。
作者（S）----------Author(s)----------
Stephen Nyangoma
举例----------Examples----------
data(liverRawData)
rawData <- liverRawData
no.peaks <- 53
no.replicates <- 2
checkNo.replicates(rawData,no.peaks,no.replicates)
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注：
注1：为了方便大家学习，本文档为生物统计家园网机器人LoveR翻译而成，仅供个人R语言学习参考使用，生物统计家园保留版权。
注2：由于是机器人自动翻译，难免有不准确之处，使用时仔细对照中、英文内容进行反复理解，可以帮助R语言的学习。
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发表于 2012-2-25 15:05:32
