findCorrPartners(attract)
findCorrPartners()所属R语言包:attract
Determines Genes with Highly Correlated Expression Profiles to a Synexpression Group
具有高度相关基因表达谱的基因决定到Synexpression集团
译者:生物统计家园网 机器人LoveR
描述----------Description----------
This function finds genes with expression profiles highly correlated to a synexpression group.
此函数查找高度相关到synexpression组表达谱基因。
用法----------Usage----------
findCorrPartners(mySynExpressionSet, myEset, removeGenes = NULL, cor.cutoff = 0.85, ...)
参数----------Arguments----------
参数:mySynExpressionSet
SynExpressionSet object.
SynExpressionSet对象。
参数:myEset
ExpressionSet object.
ExpressionSet对象。
参数:removeGenes
vector of probes that specify those genes who demonstrate little variability across the different celltypes and thus should be removed from downstream analysis.
vector指定谁演示跨不同celltypes小的变异,因此应删除下游分析这些基因的探针。
参数:cor.cutoff
numeric value specifying the correlation cut-off.
数值指定相关切断。
参数:...
additional arguments.
额外的参数。
Details
详情----------Details----------
Genes with highly correlated profiles to the synexpression groups (e.g. R > 0.85) are also likely to be integral in maintaining cell type-specific differences, however due to their lack of inclusion in resources like KEGG, would not have been picked up by the first GSEA step using findAttractors.
具有高度相关的配置文件的synexpression组的基因(如R> 0.85),也可能是在维持单元的特定类型的差异,但由于他们缺乏在KEGG资源列入积分,不会被拾起的GSEA先一步使用findAttractors。
值----------Value----------
A SynExpressionSet object which stores the genes that are highly correlated with the synexpression group provided, and their average expression profile.
一个SynExpressionSet对象存储提供synexpression组,他们的平均表达谱的高度相关的基因。
作者(S)----------Author(s)----------
Jessica Mar
举例----------Examples----------
data(subset.loring.eset)
attractor.states <- findAttractors(subset.loring.eset, "celltype", nperm=10, annotation="illuminaHumanv1.db")
remove.these.genes <- removeFlatGenes(subset.loring.eset, "celltype", contrasts=NULL, limma.cutoff=0.05)
mapk.syn <- findSynexprs("04010", attractor.states, remove.these.genes)
mapk.cor <- findCorrPartners(mapk.syn, subset.loring.eset, remove.these.genes)
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注:
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