normalize.quantiles(affy)
normalize.quantiles()所属R语言包:affy
Quantile Normalization
位数标准化
译者:生物统计家园网 机器人LoveR
描述----------Description----------
Using a normalization based upon quantiles, this function normalizes a matrix of probe level intensities.
此功能使用后位数为基础的标准化,规范化矩阵探针水平强度。
用法----------Usage----------
normalize.AffyBatch.quantiles(abatch, type=c("separate","pmonly","mmonly","together"))
参数----------Arguments----------
参数:abatch
an AffyBatch object.
AffyBatch对象。
参数:type
A string specifying how the normalization should be applied. See details for more.
一个字符串,指定应如何标准化。看到更多的细节。
Details
详情----------Details----------
This method is based upon the concept of a quantile-quantile plot extended to n dimensions. No special allowances are made for outliers. If you make use of quantile normalization either through rma or expresso please cite Bolstad et al, Bioinformatics (2003).
此方法是根据n维扩展到1位数位数图的概念。无特殊津贴离群。如果您通过rma或expresso位数标准化使用请举出Bolstad,生物信息学等(2003)。
The type argument should be one of "separate","pmonly","mmonly","together" which indicates whether to normalize only one probe type (PM,MM) or both together or separately.
类型参数应该是一个"separate","pmonly","mmonly","together"这表明是否只有一个探针类型(PM,MM)或一起或单独标准化。
值----------Value----------
A normalized AffyBatch.
一个规范化的AffyBatch。
作者(S)----------Author(s)----------
Ben Bolstad, <a href="mailto:bmbolstad.com">bmbolstad.com</a>
参考文献----------References----------
Oligonucleotide Array Data. Unpublished manuscript http://bmbolstad.com/stuff/qnorm.pdf
A Comparison of Normalization Methods for High Density Oligonucleotide Array Data Based on Bias and Variance. Bioinformatics 19(2) ,pp 185-193. http://bmbolstad.com/misc/normalize/normalize.html
参见----------See Also----------
normalize
normalize
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注:
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