本帖最后由 genechip 于 2011-1-20 20:42 编辑
糖尿病肾病(diabetic nephropathy)是一种复杂的慢性疾病。目前在欧美国发病率很高，在亚洲国家，这种复杂疾病也在以很高的比例上升。
糖尿病肾病可以由糖尿病诱导引起肾脏病变，因此叫又叫糖尿病型肾病。由于其发病机制复杂多变，目前对还没有有效的方法对此类疾病进行很好的治疗和预测。
本人想从基因芯片角度搜集一下糖尿病肾病这方面的资料。所以在GEO数据库中进行了一下简单的搜集。
结果表明，还真有从基因芯片角度做糖尿病肾病方面的研究。通过数据库查询，目前能够查询到19条糖尿病肾病方面的数据记载。
这这数据涵盖人类和鼠类，从组织到细胞，从正常-疾病到给药造模。研究者可以更加自己的需要再详细从这些数据中选择自己感兴趣的数据
下面将搜索结果列出，仅供大家参考。简单搜索会有遗漏，希望大家有新的发现可以再补上。 Results: 19
| 1: GDS3649 record: Proinsulin C-peptide and TGF-beta 1 effect on proximal tubular cell line: time course [Homo sapiens] | [url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=geoprofiles&cmd=search&term=GDS3649[ACCN]]GEO Profiles[/url], Links |
| 2: GDS1892 record: TGF-beta1 effect on renal mesangial cells [Mus musculus] | [url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=geoprofiles&cmd=search&term=GDS1892[ACCN]]GEO Profiles[/url], Links |
| 3: GDS1891 record: Glucosamine and high glucose effect on renal mesangial cells [Mus musculus] | [url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=geoprofiles&cmd=search&term=GDS1891[ACCN]]GEO Profiles[/url], Links |
| 4: GDS961 record: Diabetic [size=+0]nephropathy [Homo sapiens] | [url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=geoprofiles&cmd=search&term=GDS961[ACCN]]GEO Profiles[/url], Links |
| 5: GDS887 record: Diabetic [size=+0]nephropathy: models of type 1 and type 2 diabetes [Mus musculus] | [url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=geoprofiles&cmd=search&term=GDS887[ACCN]]GEO Profiles[/url], Links |
| 7: GSE21324 record: Gene expression profiles of the diabetic glomerular endothelial cell [Mus musculus] | Links |
| 8: GSE21785 record: Systematic analysis of a human renal transcript dataset [Homo sapiens] | Links |
| 9: GSE20636 record: Expression data from OVE26 diabetic mouse kidney [Mus musculus] | Links |
| 10: GSE20067 record: Genome wide DNA methylation profiling of diabetic [size=+0]nephropathy in type 1 diabetes mellitus [Homo sapiens] | Links |
| 11: GSE20247 record: C-peptide and/or transforming growth factor beta 1 effect on human proximal tubular cell line [Homo sapiens] | Links |
| 12: GSE4117 record: Effects of laughter on gene expression profiles of patients with type 2 diabetes [Homo sapiens] | Links |
| 13: GSE2557 record: Transcriptome Profiling of High Glucose and Glucosamine-Induced Mouse Mesangial Cells [Mus musculus] | Links |
| 14: GSE2558 record: Transcriptome profiling of Transforming Growth Factor B1-Induced Mesangial Gene Expression [Mus musculus] | Links |
| 16: GSE710 record: diabetic_[size=+0]nephropathy_streptozotocin_db_db [Mus musculus] | Links |
| 17: GPL1261 record: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array [Mus musculus] | Links |
| 18: GPL8300 record: [HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array [Homo sapiens] | Links |
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发表于 2011-1-20 20:41:12