normalize.AffyBatch.vsn(vsn)
normalize.AffyBatch.vsn()所属R语言包：vsn
Wrapper for vsn to be used as a normalization method with expresso
为VSN与EXPRESSO标准化方法被用作包装
译者：生物统计家园网 机器人LoveR
描述----------Description----------
Wrapper for vsn2 to be used as a normalization method with the expresso function of the package affy. The expresso function is deprecated, consider using justvsn instead. The normalize.AffyBatch.vsn can still be useful on its own, as it provides some additional control of the normalization process
vsn2包装使用作为与的包affy的EXPRESSO功能的归一化法。 EXPRESSO功能已过时，应考虑使用justvsn代替。的normalize.AffyBatch.vsn仍然可以对自己有用，因为它的标准化进程提供了一些额外的控制
用法----------Usage----------
normalize.AffyBatch.vsn(
abatch,
reference,
strata = NULL,
subsample = if (nrow(exprs(abatch))>30000L) 30000L else 0L,
subset,
log2scale = TRUE,
log2asymp=FALSE,
参数----------Arguments----------
参数：abatch
An object of type AffyBatch.
一个对象的类型AffyBatch。
参数：reference
Optional, a 'vsn' object from a previous fit. If this argument is specified, the data in 'x' are normalized "towards" an existing set of reference arrays whose parameters are stored in the object 'reference'. If this argument is not specified, then the data in 'x' are normalized "among themselves". See vsn2 for details.
可选的，“VSN”从以前的合适的对象。如果这个参数被指定，X的数据标准化“走向”现有的一套参考阵列的参考对象中存储的参数。如果未指定此参数，然后在X的数据归“彼此”。看到vsn2详情。
参数：strata
The 'strata' functionality is not supported, the parameter is ignored.
不支持阶层的功能，参数将被忽略。
参数：subsample
Is passed on to vsn2.
被传递到vsn2。
参数：subset
This allows the specification of a subset of expression measurements to be used for the vsn fit. The transformation with the parameters of this fit is then, however, applied to the whole dataset. This is useful for excluding expression measurements that are known to be differentially expressed or control probes that may not match the vsn model, thus avoiding that they influence the normalization process. This operates at the level of probesets, not probes. Both 'subset' and 'subsample' can be used together.
这使得规范表达测量为VSN适合用于的一个子集。然而，与此契合的参数，然后转化应用到整个数据集。这是有用的表达已知差异表达或可能不匹配的的VSN模式，从而避免他们影响标准化进程的控制探针测量除外。这工作的probesets，没有探针的水平。可以一起使用，这两个“子集”和“子样本”。
参数：log2scale
If TRUE, this will perform a global affine transform on the data to put them on a similar scale as the original non-transformed data. Many users prefer this. Fold-change estimates are not affected by this transform. In some situations, however, it may be helpful to turn this off, e.g., when comparing independently normalized subsets of the data.
如果属实，这将执行对数据的全局仿射变换把一个类似规模的非转化为原始数据。许多用户更喜欢这个。此变换倍数变化估计不会受到影响。然而，在某些情况下，它可能是有用的关闭这个功能，例如，当比较独立的数据规范化的子集。
参数：log2asymp
If TRUE, this will perform a global affine transform on the data to make the generalized log (asinh) transform be asymptotically identical to a log base 2 transform. Some people find this helpful. Only one of 'log2scale' or 'log2asymp' can be set to TRUE. Fold-change estimates are not affected by this transform.
如果属实，这将执行对数据的全局仿射变换使广义log（ASINH），改造渐近相同的2变换到一个log碱基。有些人觉得这很有帮助。只有一个的“log2scale或log2asymp可以设置为TRUE。此变换倍数变化估计不会受到影响。
参数：...
Further parameters for vsn2.
的vsn2进一步的参数。
Details
详情----------Details----------
Please refer to the Details and References sections of the man page for vsn2 for more details about this method.
请参阅手册页的详细信息和参考文献部分vsn2有关此方法的更多细节。
Important note: after calling vsn2, the function normalize.AffyBatch.vsn exponentiates the data (base 2). This is done in order to make the behavior of this function similar to the other normalization methods in affy. That packages uses the convention of taking the logarithm to base in subsequent analysis steps (e.g. in medpolish).
重要说明：后调用vsn2，normalize.AffyBatch.vsn功能exponentiates数据（基数为2）。这样做是为了使其他标准化在affy的方法类似此功能的行为。包所使用的对数为基础，在随后的分析步骤（例如medpolish）的约定。
值----------Value----------
An object of class AffyBatch. The vsn object returned, which can be used as reference for subsequent fits, is provided by description(abatch)@preprocessing$vsnReference.
对象类AffyBatch。返回vsn对象，它可以用于为reference后续配合，提供description(abatch)@preprocessing$vsnReference。
作者（S）----------Author(s)----------
D. P. Kreil <a href="http://bioinf.boku.ac.at/">http://bioinf.boku.ac.at/</a>,
Wolfgang Huber
参见----------See Also----------
vsn2
vsn2
举例----------Examples----------
## Please see vignette.[＃请参阅小插曲。]
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注：
注1：为了方便大家学习，本文档为生物统计家园网机器人LoveR翻译而成，仅供个人R语言学习参考使用，生物统计家园保留版权。
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发表于 2012-2-26 16:00:34
