for.exercise(snpStats)
for.exercise()所属R语言包:snpStats
Data for exercise in use of the snpStats package
行使在使用的snpStats包数据
译者:生物统计家园网 机器人LoveR
描述----------Description----------
These data have been created artificially from publicly available datasets. The SNPs have been selected from those genotyped by the International HapMap Project (http://www.hapmap.org) to represent the typical density found on a whole genome association chip, (the Affymetrix 500K platform, http://www.affymetrix.com/support/technical/sample\_data/500k\_hapmap\_genotype\_data.affx for a moderately sized chromosome (chromosome 10). A study of 500 cases and 500 controls has been simulated allowing for recombination using beta software from Su and Marchini (http://www.stats.ox.ac.uk/~marchini/software/gwas/hapgen.html). Re-sampling of cases was weighted in such a way as to simulate three “causal” locus on this chromosome, with multiplicative effects of 1.3, 1.4 and 1.5 for each copy of the risk allele.
这些数据已被人为造成的,从公开的数据集。由国际人类基因组单体型图计划(http://www.hapmap.org)基因密度全基因组关联芯片的典型代表,(http://www.affymetrix的Affymetrix 500K平台,已选定的SNPs 500和500例对照研究了模拟重组,允许使用beta软件,从苏的.com /支持/技术/样品\ _data/500k \ _hapmap \ _genotype \一个中等大小的染色体(10号染色体)_data.affx。 marchini(http://www.stats.ox.ac.uk/~marchini /软件/ GWAS / hapgen.html的)。在这样一种方式,来模拟三个“因果关系”这个轨迹的情况下重新取样加权染色体,1.3,1.4和1.5的乘法效应风险等位基因的每个副本。
用法----------Usage----------
data(for.exercise)
格式----------Format----------
There are three data objects in the dataset:
DataSet中的数据有三个对象:
snps.10: An object of class "SnpMatrix" containing a matrix of SNP genotype calls. Rows of the matrix correspond to subjects and columns correspond to SNPs.
snps.10:一个类的对象“SnpMatrix”呼吁含有SNP基因型矩阵。矩阵的行对应科目列对应到的SNPs。
snp.support: A conventional R data frame containing information about the SNPs typed (the chromosome position and the nucleotides corresponding to the two alleles of the SNP).
snp.support:一个传统的R数据框包含的SNPs输入(染色体上的位置和相应的SNP两个等位基因的核苷酸)信息。
subject.support: A conventional R dataframe containing information about the study subjects. There are two variables; cc gives case/control status (1=case), and stratum gives ethnicity.
subject.support:一个传统řdataframe的包含有关研究对象的信息。有两个变量;cc给案/控制状态(1 =的情况下),stratum给种族。
源----------Source----------
The data were obtained from the diabetes and inflammation laboratory (see http://www-gene.cimr.cam.ac.uk/todd)
从糖尿病和炎症的实验室获得的数据(见http://www-gene.cimr.cam.ac.uk/todd)
参考文献----------References----------
举例----------Examples----------
data(for.exercise)
snps.10
summary(snps.10)
summary(snp.support)
summary(subject.support)
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注:
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