limma2sam(siggenes)
limma2sam()所属R语言包:siggenes
limma to SAM or EBAM
limma到SAM或EBAM
译者:生物统计家园网 机器人LoveR
描述----------Description----------
Transforms the output of an analysis with limma into a SAM or EBAM object, such that a SAM or EBAM analysis, respectively, can be performed using the test statistics provided by limma.
转换分析的输出limma到SAM或EBAM对象,例如,SAM或EBAM分析,分别可以使用测试limma提供的统计数据。
用法----------Usage----------
limma2sam(fit, coef, moderate = TRUE, sam.control = samControl())
limma2ebam(fit, coef, moderate = TRUE, delta = 0.9,
ebam.control = ebamControl())
参数----------Arguments----------
参数:fit
an object of class MArrayLM, i.e.\ the output of the functions eBayes and lmFit from the limma package.
一个类的对象MArrayLM,即\输出功能eBayes和lmFitlimma包。
参数:coef
column number or name corresponding to the coefficient or contrast of interest. For details, see the argument coef of the function topTable in limma.
列的编号或名称对应的系数或利益相反。有关详细信息,请参阅参数coef函数topTablelimma。
参数:moderate
should the limma t-statistic be considered? If FALSE, the ordinary t-statistic is used in the trasnsformation to a SAM or EBAM object. If TRUE, it is expected that fit is the output of eBayes. Otherwise, fit can be the result of lmFit or eBayes.
limmat-统计量应被视为?如果FALSE,普通的t-统计在trasnsformation使用SAM或EBAM对象。如果TRUE,预计fiteBayes的输出。否则,fit能lmFit或eBayes的结果。
参数:sam.control
further arguments for the SAM analysis. See samControl for these arguments, which should only be changed if they are fully understood.
进一步的SAM分析参数。看到samControl这些参数,它应该只被改变,如果他们有充分的了解。
参数:delta
the minimum posterior probability for a gene to be called differentially expressed (or more generally, for a variable to be called significant) in an EBAM analysis. For details, see ebam. Please note that the meaning of delta differs substantially between sam and ebam
被称为一个基因的最小后验概率差异表达在EBAM分析(或更普遍的,一个被称为显着的变量)。有关详细信息,请参阅ebam。请注意,delta意义sam和ebam之间相差的
参数:ebam.control
further arguments for an EBAM analysis. See ebamControl for these arguments, which should only be changed if their meaning is fully understood.
进一步论据为EBAM分析。看到ebamControl这些参数,它应该只被改变,如果充分理解其含义。
值----------Value----------
An object of class SAM or EBAM.
一个对象类SAM或EBAM。
作者(S)----------Author(s)----------
Holger Schwender, <a href="mailto:holger.schwender@udo.edu">holger.schwender@udo.edu</a>
参考文献----------References----------
of a Microarray Experiment. JASA, 96, 1151-1160.
Expression in Microarray Experiments. Statistical Applications in Genetics and Molecular Biology, 3(1), Article 3.
Applied to the Ionizing Radiation Response. PNAS, 98, 5116-5121.
参见----------See Also----------
sam, ebam, SAM-class, EBAM-class,
sam,ebam,SAM-class,EBAM-class
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注:
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