filtermirnapath(miRNApath)
filtermirnapath()所属R语言包：miRNApath
Filter miRNApath data
过滤miRNApath数据
译者：生物统计家园网 机器人LoveR
描述----------Description----------
This method filters the miRNApath data to denote hits versus non-hits, the required distinction for running the enrichment algorithm. Data is expected to have been loaded by the loadmirnapath method.
这方法筛选miRNApath的数据来表示命中与非命中，运行富集算法所需区别。预计数据已加载loadmirnapath方法。
用法----------Usage----------
filtermirnapath(mirnaobj, pvalue=NA, expression=NA, foldchange=NA)
参数----------Arguments----------
参数：mirnaobj
An object of type mirnapath containing data resulting from the loadmirnapath method.
包含数据从loadmirnapath方法一个类型mirnapath对象。
参数：pvalue
If a p-value column has been defined in the mirnapath object, this value is used to define a subset of entries within the dataset which will be denoted as hits.
如果p值列已在mirnapath对象的定义，这个值是用来定义条目的一个子集内的点击率将作为表示数据集。
参数：expression
If an expression column has been defined in the mirnapath object, this value will be used to define entries with expression above this expression level as hits.
如果一个表达式列已在mirnapath对象的定义，这个值将被用来表达这个命中的表达水平以上定义的条目。
参数：foldchange
If a fold change column has been defined in the mirnapath object, this value is used to require hits to have a fold change greater than or equal to this value. The fold change is evaluated in both the positive and the negative, such that a foldchange=2 will allow foldchange=2 and foldchange=-2.
如果已在mirnapath对象定义倍列，该值用于需要有一个倍数的变化大于或等于这个值的命中。褶皱的变化进行评估，在双方的积极和消极的，例如，的foldchange = 2将使foldchange = 2和foldchange = -2。
Details
详情----------Details----------
This method takes a mirnapath object and assigns a flag for hits and non-hits, depending upon what filter criteria was provided. If multiple criteria are provided, they will all be collectively applied such that all criteria must be fulfilled. To that end, multiple calls to this function on the same mirnapath object should successively shrink the list of hits dependent upon the given criteria.
这种方法需要mirnapath对象和分配命中和不命中的一个标志，根据筛选条件提供。如果提供多个标准，他们将所有被统称应用等，必须满足所有条件。为此，先后多次调用这个函数相同mirnapath对象应该收缩依赖于给定的标准点击列表。
值----------Value----------
Object of type mirnapath. The state of the object will reflect that the data has been filtered.
对象类型mirnapath。对象的状态将反映的数据已被过滤。
注意----------Note----------
The method attempts to convert fold change columns appropriately so that filtering by 2 will properly mark entries greater than 2, less than -2, or less than 0.5, as the case may be.
该方法试图转换倍的变化列适当的过滤2将适当标记条目大于2，小于-2，或小于0.5，视情况而定。
作者（S）----------Author(s)----------
James M. Ward <a href="mailto:jmw86069@gmail.com">jmw86069@gmail.com</a>
参考文献----------References----------
in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways, Journal of Alzheimer's Disease 14, 27-41.
参见----------See Also----------
loadmirnapath, filtermirnapath, loadmirnatogene, loadmirnapathways
loadmirnapath，filtermirnapath，loadmirnatogene，loadmirnapathways
举例----------Examples----------
## Load miRNA expression data from AD miRNA paper[＃从公元miRNA的纸装入miRNA表达数据]
## This data contains miRNA expression data, [＃此数据包含miRNA表达数据，]
data(mirnaobj);
## Display the state, which should generally be "unfiltered"[＃显示状态，一般应是“未经过滤”]
## at this point[＃在这一点上]
mirnaobj@state;
## Display summary information about the object[＃显示对象的摘要信息。]
mirnaobj;
## Annotate hits by filtering by P-value 0.05[＃注解命中过滤的P-值0.05]
mirnaobj <- filtermirnapath( mirnaobj, pvalue = 0.05,
expression = NA, foldchange = NA );
## Display summary, noting the state is "filtered"[＃显示摘要，并指出国家“过滤”]
mirnaobj;
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注：
注1：为了方便大家学习，本文档为生物统计家园网机器人LoveR翻译而成，仅供个人R语言学习参考使用，生物统计家园保留版权。
注2：由于是机器人自动翻译，难免有不准确之处，使用时仔细对照中、英文内容进行反复理解，可以帮助R语言的学习。
注3：如遇到不准确之处，请在本贴的后面进行回帖，我们会逐渐进行修订。
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发表于 2012-2-26 01:02:29
