MethylQC(methVisual)
MethylQC()所属R语言包:methVisual
Quality controle (QC) on Methylation Data
(QC)的甲基化数据质量controle
译者:生物统计家园网 机器人LoveR
描述----------Description----------
Processing a quality control (QC) procedure on bisulafite sequences
加工的质量控制(QC)的程序bisulafite序列
用法----------Usage----------
MethylQC(refSeq, methFileDataFrame, makeChange, identity,conversion)
参数----------Arguments----------
参数:refSeq
String; genomic sequence, see selectRefSeq()
字符串;基因组序列,看到selectRefSeq()
参数:methFileDataFrame
Data frame; sequences names and their paths, see MethDataInput()
数据框序列的名称及其路径,看到MethDataInput()
参数:makeChange
Logical; if TRUE changes take place automatically, by default TRUE
逻辑;如果为TRUE的变化自动进行默认情况下,真
参数:identity
min. identity value , by default 80 percent
分钟。标识值,默认为80%
参数:conversion
min conversion rate, by default 90 percent
分钟的转化率,默认为90%
Details
详情----------Details----------
In order to avoid bad qualitative data entering this methylation analysis three measurements are made: 1) alignment check: if reverse, complement or reverse-complement 2) sequence identity between genomic sequence and every examined sequence 3) bisulfite conversion
如果相反,补充或反补2)同源性之间的基因组序列,每一个检查的顺序3)重亚硫酸盐转化对齐,以避免不好定性数据,进入这三个测量的甲基化分析:1)检查:
值----------Value----------
Returns data frame of sequences names after QC and their paths saves QCINFO.Rdata under sequence files directory
返回数据框序列的名字后,QC和它们的路径保存序列文件的目录下QCINFO.Rdata
作者(S)----------Author(s)----------
Arie Zackay <arie.zackay@mail.huji.ac.il>, Christine Steinhoff <steinhof@molgen.mpg.de>
举例----------Examples----------
## In order to use the following example [#为了使用下面的例子]
## make sure that you have writing permission under R.home()[#确保您已经下R.home书面许可()]
## directory. If you do not have permission choose your own path. [#目录。如果你没有权限选择自己的路。]
dir.create(file.path(R.home(component="home"),"/BiqAnalyzer"))
makeLocalExpDir(dataPath="/examples/BiqAnalyzer",
localDir=file.path(R.home(component="home"),"/BiqAnalyzer"))
datameth <-MethDataInput(file.path(R.home(component="home"),
"/BiqAnalyzer/PathFileTab.txt"))
refseq <- selectRefSeq(file.path(R.home(component="home"),
"/BiqAnalyzer/Master_Sequence.txt"))
QCdata <- MethylQC(refseq, datameth)
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注:
注1:为了方便大家学习,本文档为生物统计家园网机器人LoveR翻译而成,仅供个人R语言学习参考使用,生物统计家园保留版权。
注2:由于是机器人自动翻译,难免有不准确之处,使用时仔细对照中、英文内容进行反复理解,可以帮助R语言的学习。
注3:如遇到不准确之处,请在本贴的后面进行回帖,我们会逐渐进行修订。
|