mgus(survival)
mgus()所属R语言包:survival
Monoclonal gammapothy data
单克隆gammapothy数据
译者:生物统计家园网 机器人LoveR
描述----------Description----------
Natural history of 241 subjects with monoclonal gammapothy of undetermined significance (MGUS).
自然历史241科目未确定的意义(MGUS的)单克隆gammapothy。
用法----------Usage----------
mgus
mgus1
mgus2
格式----------Format----------
mgus: A data frame with 241 observations on the following 12 variables.
的MGUS:一个241以下12个变量的观测数据框。
subject id
主题ID
age in years
年龄在年
male or female
male或female
year of diagnosis
诊断年
for subjects who progress to a plasma cell malignancy
进步到浆单元恶性肿瘤的科目谁
the subtype of malignancy: multiple myeloma (MM) is the
恶性肿瘤的亚型:多发性骨髓瘤(MM)是
most common, followed by amyloidosis (AM), macroglobulinemia (MA),
最常见的,其次是淀粉样变(AM),巨球蛋白血症(马),
and other lymphprolifative (LP)
和其他lymphprolifative(LP)
days from MGUS until diagnosis of a plasma cell malignancy
天,直到诊断MGUS患者血浆单元恶性肿瘤
days from diagnosis to last follow-up
天从诊断到最后跟进
1= follow-up is until death
1 =跟进,直至死亡
albumin level at MGUS diagnosis
白蛋白水平在MGUS的诊断
creatinine at MGUS diagnosis
肌酐在MGUS的诊断
hemoglobin at MGUS diagnosis
血红蛋白在MGUS的诊断
size of the monoclonal protien spike at diagnosis
在诊断的单克隆protien穗大小
mgus1: The same data set in start,stop format. Contains the id, age, sex, and laboratory variable described above along with
mgus1:开始在相同的数据集,停止格式。包含ID,年龄,性别,和实验室变量上述随着
=1 if the interval ends in an event
= 1如果在事件结束的时间间隔
the event type
事件类型
mgus2: The mgus data, but formatted in the competing risks style. Each subject has three observations, one for time to death, one for time to MM, and one for time to a PC malignancy other than MM. Contains the id, age, sex, and laboratory variable described above along with
mgus2:的MGUS数据,但在竞争风险的样式格式化。每个主题有三个意见,死亡时间,时间为MM,和时间到一台PC以上的MM的其他恶性肿瘤之一。包含ID,年龄,性别,和实验室变量上述随着
time to event or censoring
时间到事件或审查
1 if the event occured, 0 otherwise
1,如果事件发生,否则为0
death, myeloma, or other
死亡,多发性骨髓瘤,或其他
Details
详情----------Details----------
Plasma cells are responsible for manufacturing immunoglobulins, an important part of the immune defense. At any given time there are estimated to be about 10^6 different immunoglobulins in the circulation at any one time. When a patient has a plasma cell malignancy the distribuion will become dominated by a single isotype, the product of the malignant clone, visible as a spike on a serum protein electrophoresis. Monoclonal gammapothy of undertermined significance (MGUS) is the presence of such a spike, but in a patient with no evidence of overt malignancy. This data set of 241 sequential subjects at Mayo Clinic was the groundbreaking study defining the natural history of such subjects.
浆单元负责制造免疫球蛋白,免疫防御的重要组成部分。在任何特定时间,有估计是10^6不同的循环中的免疫球蛋白,在任何一个时间。当病人有浆单元恶性肿瘤的distribuion将成为主导由单一亚型,恶性克隆的产物,作为一个尖峰血清蛋白电泳可见。的undertermined意义(MGUS的)的的单克隆gammapothy是这样一个尖峰的存在,但在病人没有明显的恶性证据。梅奥诊所的连续241科目设置这个数据是开创性的研究,确定自然历史等科目。
源----------Source----------
Mayo Clinic data courtesy of Dr. Robert Kyle.
梅奥诊所的数据由罗伯特·凯尔博士。
参考文献----------References----------
follow-up, Mayo Clinic Proc 1993; 68:26-36.
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注:
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