simulatorT1(CellNOptR)
simulatorT1()所属R语言包:CellNOptR
Simulation of a boolean model
一个布尔模型仿真
译者:生物统计家园网 机器人LoveR
描述----------Description----------
This is the simulator, inspired from BoolSimEngMKM in the Matlab CellNOpt, to be used on one time point simulations
这是模拟器,从BoolSimEngMKM在MATLAB CellNOpt的启发,在一个时间点模拟
用法----------Usage----------
simulatorT1(CNOlist, Model, SimList, indexList)
参数----------Arguments----------
参数:CNOlist
a CNOlist
1 CNOlist
参数:Model
a Model that only contains the reactions to be evaluated
只包含了一个模型,进行评估的反应
参数:SimList
a SimList as created by prep4Sim, that has also already been cut to contain only the reactions to be evaluated
创建了一个由prep4Sim的SimList,也已经减少到只包含反应进行评估
参数:indexList
an indexList as created by indexFinder
由indexFinder创建了一个indexList
Details
详情----------Details----------
Differences from the BoolSimEngMKM simulator include: the valueInhibitors has not been previously flipped; the function outputs the values across all conditions for all species in the model, instead of only for the signal species. This is because then the output of this function can be used as initial values for the version of the simulator that works on time point 2 (not implemented in this version).
从BoolSimEngMKM模拟器的差异包括:的valueInhibitors没有以前翻转;函数的输出值,在模型中的所有物种的所有条件,而不是对信号的物种只。这是因为此函数的输出可以作为版本的模拟器,工作时间2点(而不是在这个版本中实现)的初始值。
If you would like to compute the output of a model that contains some of the gates in the model but not all, we suggest that you use the function SimulateT1 and specify in the bStringT1 argument which gates you want to be included. Indeed, SimulateT1 is a wrapper around simulatorT1 that takes care of cutting the model for you before simulating it.
如果你想计算一个模型,它包含一些模型中的门,但并非所有的输出,我们建议您使用的功能SimulateT1和bStringT1参数盖茨你想指定被列入。事实上,SimulateT1是约simulatorT1包装,切割之前对你的模型,模拟它。
值----------Value----------
This function outputs a single matrix of format similar to valueSignals in the CNOlist but that contains an output for each species in the model. This matrix is the simulated equivalent of valueSignals at time 1, if you consider only the columns given by indexSignals.
此功能,输出的格式类似的CNOlist valueSignals的的单一矩阵,但包含一个模型中的每一个物种的输出。这个矩阵是的相当于时间1 valueSignals模拟的,如果只考虑由indexSignals列。
作者(S)----------Author(s)----------
C. Terfve
参考文献----------References----------
mammalian signal transduction, Molecular Systems Biology, 5:331, 2009.
参见----------See Also----------
SimulateT1, cutAndPlotResultsT1
SimulateT1,cutAndPlotResultsT1
举例----------Examples----------
#This computes the output of the full model, which is normally not done on a stand alone basis, but if you have a model and would like to visualise its output compared to your data, then this is what you should do[这种计算输出的完整的模型,这通常不是一个独立的基础上完成的,但如果你有一个模型,想形象化您的数据相比,其输出,那么这就是你应该做的]
data(CNOlistToy,package="CellNOptR")
data(ToyModel,package="CellNOptR")
indicesToy<-indexFinder(CNOlistToy,ToyModel,verbose=TRUE)
ToyFields4Sim<-prep4Sim(ToyModel)
Sim<-simulatorT1(
CNOlist=CNOlistToy,
Model=ToyModel,
SimList=ToyFields4Sim,
indexList=indicesToy)
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注:
注1:为了方便大家学习,本文档为生物统计家园网机器人LoveR翻译而成,仅供个人R语言学习参考使用,生物统计家园保留版权。
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