convert_aln_AAP(bgafun)
convert_aln_AAP()所属R语言包:bgafun
Converts alignment into a matrix using the amino acid property encoding
转换成使用氨基酸财产编码矩阵的对齐
译者:生物统计家园网 机器人LoveR
描述----------Description----------
Each residue in the alignment is represented by a vector of five continuous variables as given by Atchley et al They applied a multivariate statistic approach to reduce the information in 494 amino acid attributes into a set of five factors for each amino acid. Factor A is termed the polarity index. It correlates well with a large variety of descriptors including the number of hydrogen bond donors, polarity versus nonpolarity, and hydrophobicity versus hydrophilicity. Factor B is a secondary structure index. It represents the propensity of an amino acid to be in a particular type of secondary structure, such as a coil, turn or bend versus the frequency of it in an a-helix. Factor C is correlated with molecular size, volume and molecular weight. Factor D reflects the number of codons coding for an amino acid and amino acid composition. These attributes are related to various physical properties including refractivity and heat capacity. Factor E is related to the electrostatic charge. Gaps are represented by five zeros and should be either removed or replaced by the average of the column for a particular group.
每个残留在对齐是由他们采用多元统计方法,以减少到一组五个因素的信息,在494氨基酸属性,为每个氨基酸的Atchley等5个连续变量的向量表示。因子A被称为极性指数。它的相关性以及种类繁多,包括氢键捐助者的数量,极性与非极性,疏水性与亲水性的描述。 B因子是一个二级结构指数。它代表一种氨基酸的倾向,是在特定类型的二级结构,如线圈,与它的频率在α-螺旋的转动或弯曲。因子C与分子大小,体积和分子量。因子D反映了密码子编码的氨基酸和氨基酸组成的数量。这些属性相关的各种物理性质,化学性质,包括折射率和热容量。相关因子E的静电荷。代表五个零差距,应删除或替换一个特殊的群体的平均列。
用法----------Usage----------
convert_aln_AAP(Alignment)
参数----------Arguments----------
参数:Alignment
Alignment object read in using read.alignment function in seqinr
读在使用在seqinr read.alignment功能对齐对象
参考文献----------References----------
举例----------Examples----------
library(bgafun)
data(LDH)
data(LDH.groups)
LDH.aap=convert_aln_AAP(LDH)
dim(LDH.aap)
LDH.aap.ave=average_cols_aap(LDH.aap,LDH.groups)
dim(LDH.aap.ave)
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注:
注1:为了方便大家学习,本文档为生物统计家园网机器人LoveR翻译而成,仅供个人R语言学习参考使用,生物统计家园保留版权。
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