flu(spatstat)
flu()所属R语言包：spatstat
Influenza Virus Proteins
流感病毒蛋白质
译者：生物统计家园网 机器人LoveR
描述----------Description----------
Replicated spatial point patterns giving the locations of two different virus proteins on the membranes of cells infected with influenza virus.
复制的给予用流感病毒感染的单元的单元膜上的两个不同的病毒蛋白的位置的空间点图案。
用法----------Usage----------
data(flu)
格式----------Format----------
A hyperframe with 41 rows and four columns:
Ahyperframe有41列和四列：
List of spatial point patterns (objects of class "ppp") with points of two types, identifying the locations of two different proteins on a membrane sheet.
名单空间点模式（对象类"ppp"）与两种类型的点，确定两个不同的蛋白质的位置上的膜片。
Factor identifying whether the infecting virus was the wild type (wt) or mutant (mut1).
因子识别是否感染病毒的野生型（wt）或突变体（mut1）。
Factor identifying whether the membrane sheet was stained for the proteins M2 and M1 (stain="M2-M1") or stained for the proteins M2 and HA (stain="M2-HA").
系数确定是否膜片M2和M1（stain="M2-M1"）或染色的蛋白质染色的蛋白质M2和HA（stain="M2-HA"）。
Integer. Serial number of the microscope frame in the original experiment. Frame identifier is not unique across different values of virustype and stain.
整数。显微镜的帧中的原始实验序号。是不是唯一的不同的值virustype和stain帧识别符。
The row names of the hyperframe can be used as succinct labels in plots.
可以使用的超帧的行的名称作为简洁的图中的标签。
Details
详细信息----------Details----------
The data consist of 41 spatial point patterns, each giving the locations of two different virus proteins on the membranes of cells infected with influenza virus.
的数据包括41空间点的图案，每个给两个不同的病毒蛋白的位置用流感病毒感染的单元上的膜。
Chen et al (2008) conducted the experiment and used spatial analysis to establish evidence for an interaction between the influenza virus proteins M1 and M2 that is important for the study of viral replication.
Chen等人（2008）进行的实验和使用空间分析，以确定为流感病毒蛋白M1和M2，重要的是研究病毒复制之间的相互作用的证据。
Canine kidney cells were infected with human influenza, Udorn strain, either the wild type or a mutant which encodes a defective M2 protein. At twelve hours post-infection, membrane sheets were prepared and stained for viral proteins, using two antibodies conjugated to gold particles of two sizes (6 nanometre and 12 nanometre diameter) enabling localisation of two different proteins on each sheet. The 6 nm particles were stained for M2 (ion channel protein), while the 12 nm particles were stained either for M1 (matrix protein) or for HA (hemagglutinin). Membrane sheets were visualised in electron microscopy.
犬肾单元感染了人类流感，乌隆菌株，无论是野生型或突变体，其编码有缺陷的M2蛋白。在12小时感染后，膜片被制备和染色的病毒蛋白质，使用两种抗体共轭到金颗粒的两种尺寸（6纳米和12纳米的直径），使在每个片材的两个不同的蛋白质的定位。 6 nm的颗粒M2（离子通道蛋白）进行染色，而12 nm的颗粒M1（基质蛋白）或HA（血凝素）染色。膜片被可视化，在电子显微镜。
Experimental technique and spatial analysis of the membranes stained for M2 and M1 is reported in Chen et al (2008). Analysis of the membranes stained for M2 and HA is reported in Rossman et al (2010). The M2-HA data shows a stronger association between the two proteins which has also been observed biochemically and functionally (Rossman et al, 2010).
陈等人（2008）的实验技术和空间分析的膜染色，M2和M1报道。 M2和HA染色的膜分析报告，在罗斯曼等人（2010）。 M2-HA的数据显示，这也被观察到的生化和功能（罗斯曼等人，2010）这两种蛋白之间的关系更密切。
The dataset flu is a hyperframe with one row for each membrane sheet. The column named pattern contains the spatial point patterns of gold particle locations, with two types of points (either M1 and M2 or HA and M2). The column named virustype is a factor identifying the virus: either wild type wt or mutant mut1. The column named stain is a factor identifying whether the membrane was stained for M1 and M2 (stain="M2-M1") or stained for HA and M2 (stain="M2-HA"). The row names of the hyperframe are a succinct summary of the experimental conditions and can be used as labels in plots. See the Examples.
的数据集flu是hyperframe每个膜表一排。列名为pattern的包含空间的点图案的金粒子的位置，有两种类型的点（或者M1和M2或HA和M2）。列名为virustype的是一个识别病毒的因素：无论是野生型wt或突变的mut1。列名为stain的是一个因素，确定是否M1和M2（stain="M2-M1"）膜染色或染色的HA和M2（stain="M2-HA"）。的特超帧的行的名称是本实验条件下的简明摘要，并可以被用作绘图中所示的标签。请参阅范例。
源----------Source----------
Data generously provided by Dr G.P. Leser and Dr R.A. Lamb. Please cite Chen et al (2008) in any use of these data.
博士G.P.慷慨提供的数据LESER博士和R.A.羔羊。请举陈等人（2008）以任何方式使用这些数据。
参考文献----------References----------
The influenza virus M2 protein cytoplasmic tail interacts with the M1 protein and influences virus assembly at the site of virus budding. Journal of Virology 82, 10059–10070.
Influenza virus M2 protein mediates ESCRT-independent membrane scission Cell 142, 902–913.
实例----------Examples----------
data(flu)
flu
Y <- flu$pattern[10]
Y <- flu[10, 1, drop=TRUE]
wildM1 <- with(flu, virustype == "wt" & stain == "M2-M1")
plot(flu[wildM1, 1, drop=TRUE],
main=c("flu data", "wild type virus, M2-M1 stain"),
pch=c(3,16), cex=0.4, cols=2:3)
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注：
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发表于 2012-9-30 13:30:07
