R语言 aCGH包 colorectal()函数中文帮助文档(中英文对照)

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colorectal(aCGH)
colorectal()所属R语言包：aCGH

                                        Colorectal array CGH dataset
                                         大肠癌阵列比较基因组杂交集

                                         译者：生物统计家园网 机器人LoveR

描述----------Description----------

The colorectal dataset is an object of class aCGH. It represents a collection of 124 array CGH profiles of primary colorectal tumors and their derived attributes. Each sample was measured on the BAC clone DNA microarray with approximate resolution of 1.4 Mb per clone. There were approximately 2400 clones spotted on the array and each clone was printed in triplicates located immediately next to each other. Each array consisted of the 16 (4 by 4) subarrays. The clones were mapped on the July 03 UCSC freeze. There were a number of the discrete and continious phenotypes associated with the samples such as age, mutation status for various markers, stage, location and so on. All images were quantified and normalized by Dr. Taku Tokuyasu using custom image software SPOT and postprocessing custom software SPROC.
大肠癌的数据集是一个对象类aCGH。它代表了124阵列全息型材主要大肠肿瘤及其派生的属性的集合。每个样品测定近似分辨率1.4％MB克隆与BAC克隆DNA芯片。有阵列上发现约2400克隆，每个克隆被印在一式三份，位于彼此相邻。每个阵列16（4）子阵组成。的克隆，定位于7月03 UCSC的冻结。有数量的样品，如年龄，各种标记，舞台，位置等的突变状态的离散和305.11的表型。所有图像进行量化，并使用自定义图像处理软件SPOT和后处理定制软件存储过程由大沽Tokuyasu博士标准化。


用法----------Usage----------


data(colorectal)



源----------Source----------

These data were generated at Dr. Fred Waldman's lab at UCSF Cancer Center by K. Nakao and K. Mehta. The manuscript describing the data and the analysis are described in High-resolution analysis of DNA copy number alterations in colorectal cancer by array-based comparative genomic hybridization, Carcinogenesis, 2004, Nakao et. al.
这些数据生成在弗雷德瓦尔德曼博士的实验室在加州大学旧金山分校癌症中心由K.中尾和K.梅塔。在高分辨率的大肠癌的DNA拷贝数改变的分析，基于阵列的比较基因组杂交，致癌性，2004年，中尾等手稿描述的数据和分析。等。


参考文献----------References----------

alterations in colorectal cancer by array-based comparative genomic hybridization, Carcinogenesis, 2004 Jain et. al, Fully automatic quantification of microarray image data, Genome Research, 2003

参见----------See Also----------

aCGH plotGenome
aCGHplotGenome


举例----------Examples----------



data(colorectal)
## WARNING: plotting the heatmap takes some time[＃警告：绘制热图需要一些时间]
plot(colorectal)
plotGenome(colorectal[,1:2])


转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。


注：
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