The package provides some functionalities that can be useful for the analysis of high-density tiling microarray data (such as Affymetrix genechips) for measuring transcript abundance and architecture. The main functionalities of the package are:
该软件包提供了一些功能,可以为高密度平铺测量转录丰度和结构(如Affymetrix的基因芯片)芯片的数据分析是有用的。包的主要功能是:
The segmentation class for representing partitionings of a linear series of data (such as microarray intensity readings along a chromosome strand).
分割类为代表的一系列数据(如沿染色体链中的芯片强度读数)的线性partitionings。
The function segment for fitting piecewise constant models using a dynamic programming algorithm that is both fast and exact, and confint for calculating confidence intervals using the strucchange package. Please see the vignette Segmentation demo in the file inst/doc/segmentation.pdf (source file inst/scripts/segmentation.Rnw).
segment函数拟合分段常数模型,采用动态规划算法是快速,准确,和confint计算置信区间使用strucchange包。请看到INST / DOC / segmentation.pdf的的(源文件INST /脚本/ segmentation.Rnw)的文件的小插曲分割演示。
The function plotAlongChrom for generating pretty plots of segmentations along with genomic features. Please also see the vignette Segmentation demo.
功能plotAlongChrom随着基因功能产生漂亮的图分割。请也看到了的暗角分割演示。
The function normalizeByReference for probe-sequence dependent response adjustment from a (set of) reference hybridizations. Please see the vignette Assessing signal/noise ratio before and after normalization in the file inst/doc/assessNorm.pdf (source file inst/scripts/assessNorm.Rnw).
功能normalizeByReference(套)参考杂交探针序列依赖反应调整。请参阅文件中的标准化前后的小插曲,评估信号/噪声比INST / DOC / assessNorm.pdf的的(INST /脚本/ assessNorm.Rnw)的源文件。