sampleSize.matched(sizepower)
sampleSize.matched()所属R语言包：sizepower
Sample Size Calculation for Matched-Pairs Designs in Microarray Studies
样本大小匹配对芯片研究设计计算
译者：生物统计家园网 机器人LoveR
描述----------Description----------
This routine computes the sample size n required to achieve a specified power level for a matched-pairs design in which differential expression between n treatment units and n matched control units is of interest. The total number of experimental units for the study is 2n.
常规计算样本大小n需要一个匹配的对中差n治疗单位和n匹配的控制单元之间的利益表达的是设计，以实现指定的功率水平。研究的试点单位总数是2n。
用法----------Usage----------
sampleSize.matched(ER0, G0, power, absMu1, sigmad)
参数----------Arguments----------
参数：ER0
mean number of false positives.
平均误报数量。
参数：G0
anticipated number of genes in the experiment that are not differentially expressed.
预计数量在实验都没有差异表达的基因。
参数：power
specified power level for an individual gene, which represents the expected proportion of differentially expressed genes that will be declared as such by the tests.
指定一个单独的基因，它代表了预期的比例差异表达的基因测试将被宣布为等功率水平。
参数：absMu1
absolute mean difference in log-expression between treatment and control units as postulated under the alternative hypothesis H1.
log表达绝对的治疗和控制单元之间的平均差异为假设下的替代假设H1。
参数：sigmad
anticipated standard deviation of the difference in log-expression between matched treatment and control units.
预计在log表达匹配的治疗和控制单元之间的差异的标准偏差。
值----------Value----------
参数：n
sample size for each group.
每个组的样本大小。
参数：d
statistical difference between treatment and control conditions under H1 (i.e. d=absMu1/sigmad).
根据上半年的治疗和控制条件之间的统计学差异（即d=absMu1/sigmad）。
注意----------Note----------
Examples and explainations can be found in http://www.biostat.harvard.edu/people/faculty/mltlee/pdf/Web-sampsize-matched050510.pdf.
例子和解释相关可以发现在http://www.biostat.harvard.edu/people/faculty/mltlee/pdf/Web-sampsize-matched050510.pdf。
作者（S）----------Author(s)----------
Weiliang Qiu (<a href="mailto:weiliang.qiu@gmail.com">weiliang.qiu@gmail.com</a>),
Mei-Ling Ting Lee (<a href="mailto:meilinglee@sph.osu.edu">meilinglee@sph.osu.edu</a>),
George Alex Whitmore (<a href="mailto:george.whitmore@mcgill.ca">george.whitmore@mcgill.ca</a>)
参考文献----------References----------
Analysis of Microarray Gene Expression Data. Kluwer Academic Publishers, ISBN 0-7923-7087-2.
Power and sample size for DNA microarray studies. Statistics in Medicine, 21:3543-3570.
参见----------See Also----------
power.randomized, power.matched power.multi, sampleSize.randomized
power.randomized，power.matchedpower.multi，sampleSize.randomized
举例----------Examples----------
sampleSize.matched(ER0=1, G0=2000, power=0.9, absMu1=1, sigmad=0.5)
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注：
注1：为了方便大家学习，本文档为生物统计家园网机器人LoveR翻译而成，仅供个人R语言学习参考使用，生物统计家园保留版权。
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发表于 2012-2-26 14:25:37
