getChangedRegions(quantsmooth)
getChangedRegions()所属R语言包：quantsmooth
getChangedRegions
getChangedRegions
译者：生物统计家园网 机器人LoveR
描述----------Description----------
retrieve regions of interest in a vector of intensities using quantile smoothing
检索使用位数平滑的强度矢量区域的利益
用法----------Usage----------
getChangedRegions(intensities, positions, normalized.to=1, interval, threshold, minlength=2, ...)
参数----------Arguments----------
参数：intensities
numeric vector
数字向量
参数：positions
numeric vector of the same length as intensities. If this argument is not given the results contain the indexes of the intensities vector, else the values in positions are used. Both vectors are sorted in the order of positions.
数字向量的长度和强度相同。如果该参数没有给出的结果中包含intensities向量的指标，否则positions用于值。这两个向量在positions的顺序排序。
参数：normalized.to
numeric, reference value. Changes are compared to this value
数字参考价值。更改这个值相比
参数：interval
numeric [0,1], bandwidth around reference. If the smoothed line at the higher quantile drops below the normalized.to value, a deleted region is recognized, and vice versa.
数字[0,1]，各地参考带宽。如果在下面normalized.to价值高的位数下降的平滑线，确认已删除的区域，反之亦然。
参数：threshold
numeric, if the median smoothed value drops below normalized.to - threshold, or above normalized.to + threshold a changed region is called
数字，如果中位数的平滑值下降到低于normalized.to - threshold，或以上normalized.to + threshold变了一个区域被称为
参数：minlength
integer, not used currently
整数，而不是目前使用
参数：...
extra arguments for quantsmooth function
quantsmooth函数的额外参数
Details
详情----------Details----------
This function uses quantsmooth to detect regions in the genome that are abnormal. If interval is set then a smoothed line is calculated for tau = 0.5 - interval/2, and a region is determined as upregulated if this line is above the reference. Down regulation is determined when the smoothed line for tau = 0.5 + interval/2 is below the reference value. If threshold is set then a smoothed line is calculated for tau = 0.5 and up- or down regulation are determined when this line is outside the range [normalized.t - threshold:normalized.to + threshold]
此功能使用quantsmooth检测基因组中是不正常的区域。 interval如果tau = 0.5 - interval/2被设置，那么计算一个平滑的线，如果这条线是参考以上的区域确定为上调。下调时的光滑tau = 0.5 + interval/2“线以下的参考价值。如果threshold设置，然后计算平滑线tau = 0.5“向上或向下调节时，这条线范围以外的[normalized.t - threshold:normalized.to + threshold]
值----------Value----------
A data.frame with 3 colums is returned. Each row contains a region with columns up, start and end. start and end indicate positions in the vector of the first and last position that were up- or downregulated
一个与3 colums数据框返回。每一行包含一个列的区域up，start和end。 start和end显示的第一个和最后一个位置向量中的位置上调或下调
作者（S）----------Author(s)----------
Jan Oosting
举例----------Examples----------
data(chr14)
getChangedRegions(ill.cn[,1],ill.pos,normalized.to=2,interval=0.5)
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注：
注1：为了方便大家学习，本文档为生物统计家园网机器人LoveR翻译而成，仅供个人R语言学习参考使用，生物统计家园保留版权。
注2：由于是机器人自动翻译，难免有不准确之处，使用时仔细对照中、英文内容进行反复理解，可以帮助R语言的学习。
注3：如遇到不准确之处，请在本贴的后面进行回帖，我们会逐渐进行修订。
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发表于 2012-2-26 11:43:03
