loadmirnapathways(miRNApath)
loadmirnapathways()所属R语言包:miRNApath
Load gene to pathway associations for miRNApath
加载基因途径协会为miRNApath
译者:生物统计家园网 机器人LoveR
描述----------Description----------
This method loads associations between genes and the pathways to which they belong.
这种方法载入协会之间的基因和它们所属的途径。
用法----------Usage----------
loadmirnapathways(mirnaobj, pathwayfile, genecol="Entrez Gene ID",
pathwaycol="PATHWAY", columns=c(), pathwayidcol=NA)
参数----------Arguments----------
参数:mirnaobj
An object of type mirnapath containing data resulting from the loadmirnapath method.
包含数据从loadmirnapath方法一个类型mirnapath对象。
参数:pathwayfile
The file containing the gene to pathway associations.
该文件包含的基因通路协会。
参数:genecol
The name of the column header which contains the gene names associated with pathway data.
列标题的名称,其中包含与通路数据关联的基因名称。
参数:pathwaycol
The name of the column header which contains the pathway names.
其中包含的通路名称的列标题的名称。
参数:columns
The names of any additional columns in the file being read which should equate with the mirnapath object.
正在读取文件中的任何其他列的名称应等同与mirnapath对象。
参数:pathwayidcol
The (optional) column header for IDs associated with the pathway names.
通路名称的ID的列标题(可选)。
Details
详情----------Details----------
The data loaded is expected to have gene names which exactly match those gene names loaded by loadmirnatogene.
数据加载,预计将有基因完全匹配的名字载入loadmirnatogene这些基因名称。
值----------Value----------
The method returns an object of type mirnapath, a list with components:
该方法返回一个对象,一个组件的列表类型mirnapath:
参数: mirnaTable
data.frame containing the miRNA results data
数据框包含miRNA的结果数据
参数: columns
list containing the names of required column headers associated to the actual column header supplied in the dataset contained in mirnaTable. Required headers: mirnacol, assayidcol. Optional headers: groupcol, pvaluecol, foldchangecol, expressioncol, filterflagcol
包含关联到实际列头在包含在mirnaTable数据集提供所需的列头名的名单。所需头文件:mirnacol,assayidcol。可选的标题:groupcol,pvaluecol,foldchangecol,expressioncol,filterflagcol
参数: groupcount
the number of groups contained in mirnaTable using the groupcol, if supplied
包含在mirnaTable使用groupcol,如果提供的组数
参数: state
the current state of the object, using the following values in order of progress through the typical workflow: unfiltered, filtered, enriched.
对象的当前状态,为了进步,通过典型的工作流程使用以下值:未经过滤,过滤,丰富。
作者(S)----------Author(s)----------
James M. Ward <a href="mailto:jmw86069@gmail.com">jmw86069@gmail.com</a>
参考文献----------References----------
in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways, Journal of Alzheimer's Disease 14, 27-41.
参见----------See Also----------
loadmirnapath, filtermirnapath, loadmirnatogene, loadmirnapathways, runEnrichment
loadmirnapath,filtermirnapath,loadmirnatogene,loadmirnapathways,runEnrichment
举例----------Examples----------
## Load miRNA expression data from AD miRNA paper[#从公元miRNA的纸装入miRNA表达数据]
## This data contains miRNA expression data, [#此数据包含miRNA表达数据,]
data(mirnaobj);
## Write a file as example of required input[#写的一个文件所需的输入为例]
write.table(mirnaobj@mirnaPathways, file = "mirnaPathways.txt",
quote = FALSE, row.names = FALSE, col.names = TRUE, na = "",
sep = "\t");
## Load the gene to pathway associations[#加载基因通路协会]
mirnaobj <- loadmirnapathways( mirnaobj = mirnaobj,
pathwayfile = "mirnaPathways.txt",
pathwaycol = "Pathway Name", genecol = "Entrez Gene ID");
## Display summary, noting the number of genes reported[#显示摘要,并指出基因数目报道]
mirnaobj;
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注:
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