IsoGeneGUI-package(IsoGeneGUI)
IsoGeneGUI-package()所属R语言包:IsoGeneGUI
IsoGeneGUI Graphical User Interface for the IsoGene package
IsoGeneGUI为IsoGene包的图形用户界面
译者:生物统计家园网 机器人LoveR
描述----------Description----------
The IsoGene Graphical User Interface (IsoGene-GUI) is a user friendly interface of the IsoGene package which is aimed to identify for genes with a monotonic trend in the expression levels with respect to the increasing doses using several test statistics: global likelihood ratio test (E2), Bartholomew 1961, Barlow et al. 1972 and Robertson et al. 1988), Williams (1971, 1972), Marcus (1976), the M (Hu et al. 2005) and the modified M (Lin et al. 2007).
IsoGene图形用户界面(IsoGene GUI)是一个用户友好界面的IsoGene包旨在确定基因与单调增加剂量使用多种测试统计中的表达水平与趋势:全球似然比检验( E2),巴塞洛缪1961年,巴洛等。 1972年,罗伯逊等。 1988年),威廉姆斯(1971年,1972年),马库斯(1976年),在M(胡等,2005)和改良米(林等,2007)。
The p-values of the global likelihood ratio test (E2) are obtained using the exact distribution and permutation. The other four test statistics are obtained using permutation .
全球似然比检验(E2),p值获得使用的确切分布和排列。其他四个测试统计得到使用置换。
Several p-values adjustment are provided: Bonferroni, Holm (1979), Hochberg (1988), and Sidak procedures for controlling the family-wise Type I error rate (FWER), and BH (Benjamini and Hochberg 1995) and BY (Benjamini and Yekutieli 2001) procedures are used for controlling the FDR.
几个P-值调整:邦弗朗尼,霍尔姆(1979),Hochberg(1988),和控制家庭明智的类型错误率(FWER),波黑(Benjamini和Hochberg 1995年)和Sidak程序(Benjamini和yekutieli 2001年)的程序,用于控制FDR。
Details
详情----------Details----------
The IsoGene Graphical User Interface (IsoGene-GUI) is a user friendly interface of the IsoGene package.
IsoGene图形用户界面(IsoGene GUI)是一个用户界面友好的IsoGene包。
作者(S)----------Author(s)----------
Author: Setia Pramana
Maintainer: Setia Pramana <setia.pramana@uhasselt.be>
参考文献----------References----------
Under Order Restriction. New York: Wiley.
332.
testing under dependency. ANN STAT, 29 (4), 1165-1188.
response effects on gene expression data with comparison of two microarray platforms. Bioinformatics, 21(17), 3524-3529.
T., Geerts, T. and Bijnens, L. (2007) Testing for trends in dose-response microarray experiments: A comparison of several testing procedures, multiplicity and resampling- based inference. Statistical Applications in Genetics and Molecular Biology, 6(1), Article 26.
ordered alternative. Biometrika, 63, 177-83.
Wiley.
65-70.
Vol. 75: 800-802.
levels are compared with a zero dose control. Biometrics, 27, 103-117.
metrics, 28, 519-531.
举例----------Examples----------
## Not run: [#无法运行:]
library(IsoGeneGUI)
IsoGeneGUI()
## End(Not run)[#结束(不运行)]
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注:
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