找回密码
 注册
查看: 467|回复: 0

R语言 isobar包 ratiosummarization()函数中文帮助文档(中英文对照)

[复制链接]
发表于 2012-2-25 22:40:48 | 显示全部楼层 |阅读模式
ratiosummarization(isobar)
ratiosummarization()所属R语言包:isobar

                                        protein and peptide ratios
                                         蛋白质和多肽的比例

                                         译者:生物统计家园网 机器人LoveR

描述----------Description----------

A set of functions to create ratios within groups and summarize them.  proteinRatios serves as hub and calls combn.matrix,  combn.protein.tbl and summarize.ratios successively. It can be  used to calculate intra-class and inter-class ratios, to assess ratios and variability within and over cases.
一组函数来创建组内的比率,并总结他们。 proteinRatios作为枢纽和调用combn.matrix,combn.protein.tbl和summarize.ratios先后。它可以用来计算类内和类间的比率,评估及以上情况比率和变异。


用法----------Usage----------


proteinRatios(ibspectra, noise.model, reporterTagNames = NULL, proteins = reporterProteins(proteinGroup(ibspectra)), peptide = NULL, cl = classLabels(ibspectra), method = "global", symmetry = FALSE, summarize = FALSE, summarize.method = "mult.pval", min.detect = NULL, strict.sample.pval = TRUE, strict.ratio.pval = TRUE, orient.div = 0, sign.level = 0.05, sign.level.rat = sign.level, sign.level.sample = sign.level, ratiodistr = NULL, variance.function = "maxi", combine=FALSE,
p.adjust = NULL, reverse=FALSE, combn=NULL, ...)

combn.matrix(x, method = "global", cl = NULL)

combn.protein.tbl(ibspectra, noise.model, ratiodistr, proteins = NULL, cmbn, peptide = NULL, modif = NULL, symmetry = FALSE, reverse = FALSE, variance.function = "maxi", ...)

summarize.ratios(ratios, summarize.method, min.detect, n.combination, strict.sample.pval = TRUE, strict.ratio.pval = TRUE, orient.div = 0, sign.level = 0.05, sign.level.rat = sign.level, sign.level.sample = sign.level, variance.function = "maxi", ratiodistr, p.adjust = NULL)




参数----------Arguments----------

参数:ibspectra
IBSpectra object
IBSpectra对象


参数:x
for combn.matrix: reporter names. See reporterTagNames. argument of proteinRatios.
combn.matrix:记者名称。看到reporterTagNames。参数proteinRatios。


参数:ratios
result of combn.protein.tbl
导致的combn.protein.tbl


参数:cmbn
result of combn.matrix
导致的combn.matrix


参数:combn
result of combn.matrix
导致的combn.matrix


参数:noise.model
NoiseModel for spectra variances
NoiseModel的光谱差异


参数:reporterTagNames
Reporter tags to use. By default all reporterTagNames of ibspectra object.
记者标签使用。默认情况下,所有reporterTagNames ibspectra对象。


参数:proteins
proteins for which ratios are calculated - defaults to all  proteins with peptides specific to them.
比率计算的蛋白质 - 默认为所有的蛋白质与他们特定的肽。


参数:peptide
peptides for which ratios are calculated.
肽比率计算。


参数:modif
Modification.
修改。


参数:cl
Class labels. See also ?classLabels.  
类的标签。还可以看吗?classLabels。


参数:method
"global", "interclass", or "intra-class". Defines which ratios are computed, based on class labels cl
“全球”,“组间”,或“内部类”。定义比率计算,基于类的标签CL


参数:symmetry
If true, reports also the inverse ratio
如果情况属实,报告还反比


参数:summarize
If true, ratios for each protein are summarized.
如果情况属实,每个蛋白的比率进行了总结。


参数:summarize.method
"isobar", for now.
“压线”,现在。


参数:min.detect
How many times must a ratio for a protein be present when summarizing? When NULL, defaults to the maximum number of combinations.
必须的一种蛋白质的比例是多少次时总结?当空,默认的最大数量的组合。


参数:strict.sample.pval
If true, missing ratios are penalized by giving  them a sample.pval of 0.5.
如果为true,丢失率,给他们一个0.5 sample.pval处罚。


参数:strict.ratio.pval
If true, take all ratios into account. If false, only take ratios into account which are in the same direction as the majority of  ratios
如果情况属实,考虑到所有的比率。如果为false,只考虑在同一方向,为广大的比率的比率


参数:orient.div
Number of ratios which might go in the wrong direction.
数比率可能在错误的方向去。


参数:sign.level
Significance level
显着性水平


参数:sign.level.rat
Significance level on ratio p-value
比p值显着性水平


参数:sign.level.sample
Significance level on sample p-value
对样品的p值的显着性水平


参数:ratiodistr
Protein ratio distribution
蛋白质比例分布


参数:variance.function
Variance function
方差函数


参数:...
Passed to estimateRatio()
传递到estimateRatio的()


参数:combine
If true, a single ratio for all proteins and peptides, resp., is calculated. See estimateRatio.
如果情况属实,所有的蛋白质和多肽,分别为单比率,计算。看到estimateRatio。


参数:p.adjust
Set to one of p.adjust.methods to adjust ratio p-values for multiple comparisions. See p.adjust.
设置p.adjust.methods比p-值调整为多重比较。看到p.adjust。


参数:reverse
reverse
逆转


参数:n.combination
numbero fo combinations possible
numbero FO组合可能


值----------Value----------

'data.frame':        11 variables:
“数据框”:11个变量:


参数:lratio
log ratio
登录率


参数:variance
variance
方差


参数:n.spectra
Number of spectra used for quantification
光谱定量号码


参数:p.value.rat
Signal p-value (NA if ratiodistr is missing)
信号p值(不适用,如果ratiodistr缺少)


参数:p.value.sample
Sample p-value (NA if ratiodistr is missing)
样品的p值(不适用,如果ratiodistr丢失)


参数:is.significant
Is the ratio significant? (NA if ratiodistr is missing)
是显著的比例? (不适用,如果ratiodistr丢失)


参数:protein
Protein quantified
蛋白质定量


参数:r1
r1
R1


参数:r2
r2
R2


作者(S)----------Author(s)----------



Florian P Breitwieser, Jacques Colinge




参见----------See Also----------

IBSpectra, isobar-preprocessing isobar-analysis
IBSpectra,压线,预处理等压线分析


举例----------Examples----------



combn.matrix(114:117,method="interclass",cl=as.character(c(1,1,2,2)))
combn.matrix(114:117,method="interclass",cl=as.character(c(1,1,2,2)))
combn.matrix(114:117,method="global")

data(ibspiked_set1)
data(noise.model.hcd)

ceru.proteins <- c("P13635","Q61147")
proteinRatios(ibspiked_set1,noise.model=noise.model.hcd,proteins=ceru.proteins,cl=c("T","T","C","C"),method="interclass",summarize=TRUE)


转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。


注:
注1:为了方便大家学习,本文档为生物统计家园网机器人LoveR翻译而成,仅供个人R语言学习参考使用,生物统计家园保留版权。
注2:由于是机器人自动翻译,难免有不准确之处,使用时仔细对照中、英文内容进行反复理解,可以帮助R语言的学习。
注3:如遇到不准确之处,请在本贴的后面进行回帖,我们会逐渐进行修订。
回复

使用道具 举报

您需要登录后才可以回帖 登录 | 注册

本版积分规则

手机版|小黑屋|生物统计家园 网站价格

GMT+8, 2025-2-5 10:46 , Processed in 0.022494 second(s), 16 queries .

Powered by Discuz! X3.5

© 2001-2024 Discuz! Team.

快速回复 返回顶部 返回列表