geneSim(GOSemSim)
geneSim()所属R语言包:GOSemSim
Semantic Similarity Between two Genes
两个基因之间的语义相似性
译者:生物统计家园网 机器人LoveR
描述----------Description----------
Given two genes, this function will calculate the semantic similarity between them, and return their semantic similarity and the corresponding GO terms
鉴于这两个基因,此函数将计算它们之间的语义相似性,并返回他们的语义相似性和相应的GO术语
用法----------Usage----------
geneSim(gene1, gene2, ont = "MF", organism="human",measure="Wang", drop= "IEA", combine="rcmax.avg")
参数----------Arguments----------
参数:gene1
Entrez gene id.
Entrez基因身份证。
参数:gene2
Another entrez gene id.
另一Entrez基因ID。
参数:ont
One of "MF", "BP", and "CC" subontologies.
“MF”,“BP”,“消委会”subontologies的之一。
参数:organism
One of "anopheles", "arabidopsis", "bovine", "canine", "chicken", "chimp", "coelicolor", "ecolik12", "ecsakai", "fly", "human", "malaria", "mouse", "pig", "rat", "rhesus", "worm", "xenopus", "yeast" and "zebrafish".
“按蚊”,“拟南芥”,“牛”,“犬”,“鸡”,“黑猩猩”,“霉菌”,“ecolik12”,“ecsakai”,“飞” ,“人”,“疟疾”,“老鼠”,“猪”,“鼠”,“猴”,“蠕虫”,“爪”,“酵母”和“斑马鱼” ;
参数:measure
One of "Resnik", "Lin", "Rel", "Jiang" and "Wang" methods.
“雷斯尼克”,“林”,“相对”,“江”和“王”的方法。
参数:drop
A set of evidence codes based on which certain annotations are dropped. Use NULL to keep all GO annotations.
在此基础上的一组证据代码的某些注解下降。使用NULL,让所有的GO注释。
参数:combine
One of "max", "average", "rcmax", "rcmax.avg" methods, for combining semantic similarity scores of multiple GO terms associated with protein or multiple proteins assiciated with protein cluster.
“最大”,“平均”,“rcmax”,“rcmax.avg”的方法,assiciated聚类与蛋白质结合语义相似度与蛋白质或多种蛋白质有关的多个GO条款。
值----------Value----------
参数:geneSim
Semantic similarity.
语义相似性。
参数:GO1
Corresponding GO terms for gene1.
gene1相应的GO术语。
参数:GO2
Corresponding GO terms for gene2.
gene2相应的GO术语。
参考文献----------References----------
A new method to measure the semantic similarity of go terms Bioinformatics (Oxford, England), 23:0 1274–81, May 2007. ISSN 1460-2059 http://www.ncbi.nlm.nih.gov/pubmed/17344234 PMID: 17344234
Semantic similarity measures as tools for exploring the gene ontology Pacific Symposium on Biocomputing Pacific Symposium on Biocomputing, 2003:601-12, ISSN 1793-5091 http://www.ncbi.nlm.nih.gov/pubmed/12603061 PMID: 12603061
参见----------See Also----------
goSim mgoSim mgeneSim clusterSim mclusterSim
goSimmgoSimmgeneSimclusterSimmclusterSim
举例----------Examples----------
geneSim("241", "251", ont="MF", organism="human", measure="Wang")
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注:
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