normalize.invariantset(affy)
normalize.invariantset()所属R语言包:affy
Invariant Set normalization
不变集归
译者:生物统计家园网 机器人LoveR
描述----------Description----------
Normalize arrays in an AffyBatch using an invariant set.
AffyBatch使用不变集标准化阵列。
用法----------Usage----------
normalize.AffyBatch.invariantset(abatch, prd.td = c(0.003, 0.007),
verbose = FALSE,
baseline.type = c("mean","median","pseudo-mean","pseudo-median"),
type = c("separate","pmonly","mmonly","together"))
normalize.invariantset(data, ref, prd.td=c(0.003,0.007))
参数----------Arguments----------
参数:abatch
an AffyBatch object.
AffyBatch对象。
参数:data
a vector of intensities on a chip (to normalize to the reference).
芯片上的向量强度(标准化参考)。
参数:ref
a vector of reference intensities.
参考强度矢量。
参数:prd.td
cutoff parameter (details in the bibliographic reference).
截止参数(书目参考的细节)。
参数:baseline.type
specifies how to determine the baseline array.
指定如何确定基线阵列。
参数:type
a string specifying how the normalization should be applied. See details for more.
一个字符串,指定应如何标准化。看到更多的细节。
参数:verbose
logical indicating printing throughout the normalization.
印刷整个标准化的逻辑表示。
Details
详情----------Details----------
The set of invariant intensities between data and ref is found through an iterative process (based on the respective ranks the intensities). This set of intensities is used to generate a normalization curve by smoothing.
组不变data和ref通过一个反复的过程(根据所属职级的强度)之间的强度。这组的强度是用来生成由平滑标准化曲线。
The type argument should be one of "separate","pmonly","mmonly","together" which indicates whether to normalize only one probe type (PM,MM) or both together or separately.
type参数应该是一个"separate","pmonly","mmonly","together"这表明是否只有一个探针类型(PM,MM)或一起或单独标准化。
值----------Value----------
Respectively a AffyBatch of normalized objects, or a vector of normalized intensities, with an attribute "invariant.set" holding the indexes of the 'invariant' intensities.
AffyBatch归对象,或归强度的矢量属性“invariant.set”持有“不变”的强度指标,分别。
作者(S)----------Author(s)----------
L. Gautier <laurent@cbs.dtu.dk>
(Thanks to Cheng Li for the discussions about the algorithm.)
参考文献----------References----------
oligonucleotides arrays: model validation, design issues and standard error application. Genome Biology 2001, 2(8):research0032.1-0032.11
参见----------See Also----------
normalize to normalize AffyBatch objects.
normalize标准化AffyBatch对象。
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注:
注1:为了方便大家学习,本文档为生物统计家园网机器人LoveR翻译而成,仅供个人R语言学习参考使用,生物统计家园保留版权。
注2:由于是机器人自动翻译,难免有不准确之处,使用时仔细对照中、英文内容进行反复理解,可以帮助R语言的学习。
注3:如遇到不准确之处,请在本贴的后面进行回帖,我们会逐渐进行修订。
|