aCGH.process(aCGH)
aCGH.process()所属R语言包:aCGH
Process data in aCGH object
在aCGH对象的过程数据
译者:生物统计家园网 机器人LoveR
描述----------Description----------
This function takes object of class aCGH, and filters clones based on their mapping information and proportion missing. It also average duplicated clones and reports quality statistic.
此功能类aCGH,并根据他们的映射信息和比例失踪过滤器克隆的对象。它还平均重复克隆和报告的质量统计。
用法----------Usage----------
aCGH.process(aCGH.obj, chrom.remove.threshold = 24,
prop.missing = 0.25, sample.quality.threshold = 0.4,
unmapScreen=TRUE, dupRemove = TRUE)
参数----------Arguments----------
参数:aCGH.obj
Object of class aCGH
对象的类aCGH
参数:chrom.remove.threshold
Chromosomes are ordered and numbered as usual, except for X and Y chromosome, which in for Homo sapiens genome have numbers 23 and 24 repsectivelly, in for Mus musculus 20 and 21, etc.
像往常一样的染色体排序和编号,除X和Y染色体,在智人基因组有数字repsectivelly 23日和24日在小家鼠20日和21等,
参数:prop.missing
Clones are screened out and if the proportion missing in the samples is prop.missing they are removed.
克隆被筛选出,如果样品中失踪的比例是prop.missing删除它们。
参数:sample.quality.threshold
Mark those samples that have their proportion of missing values sample.quality.threshold.
标记这些样本有遗漏值sample.quality.threshold比例。
参数:unmapScreen
Indicator for whether clones with incomplete mapping information should be removed from the dataset. Note that leaving them in may cause plotting routines fail. Defaults to TRUE
是否映射信息不完全的克隆指标应当从DataSet中删除。请注意,使他们在可能导致图例程失败。默认为true
参数:dupRemove
Indicator for whether clones with duplicate names should be averaged and removed from the dataset leaving only one occurence of each duplicated set.Defaults to TRUE
指标名称重复的克隆是否应平均,并从DataSet中删除,只留下一个的发生每个重复set.Defaults的为TRUE
值----------Value----------
Object of class aCGH.
对象类aCGH。
作者(S)----------Author(s)----------
Jane Fridlyand, Peter Dimitrov
参见----------See Also----------
aCGH
aCGH
举例----------Examples----------
datadir <- system.file(package = "aCGH")
datadir <- paste(datadir, "/examples", sep="")
clones.info <-
read.table(file = file.path(datadir, "clones.info.ex.txt"),
header = TRUE, sep = "\t", quote="", comment.char="")
log2.ratios <-
read.table(file = file.path(datadir, "log2.ratios.ex.txt"),
header = TRUE, sep = "\t", quote="", comment.char="")
pheno.type <- read.table(file = file.path(datadir, "pheno.type.ex.txt"),header = TRUE, sep = "\t", quote="", comment.char="")
ex.acgh <- create.aCGH(log2.ratios, clones.info, pheno.type)
ex.acgh <-
aCGH.process(ex.acgh, chrom.remove.threshold = 23, prop.missing = .25,
sample.quality.threshold = .4, unmapScreen=TRUE, dupRemove = FALSE)
ex.acgh
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注:
注1:为了方便大家学习,本文档为生物统计家园网机器人LoveR翻译而成,仅供个人R语言学习参考使用,生物统计家园保留版权。
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