test.allele.switch(snpStats)
test.allele.switch()所属R语言包：snpStats
Test for switch of alleles between two collections
测试的两个集合之间的基因开关
译者：生物统计家园网 机器人LoveR
描述----------Description----------
When testing genotype data derived from different platforms or scoring algorithms a common problem is switching of alleles. This function provides a diagnostic for this. Input can either be two objects of class "SnpMatrix" to be examined, column by column, for allele switching, or a single "SnpMatrix" object together with an indicator vector giving group membership for its rows.
当测试来自不同的平台或得分的算法，一个共同的问题是基因开关的基因型数据。此功能提供一个诊断。输入可以是两个对象类"SnpMatrix"进行审查，由列，等位基因交换，或单一"SnpMatrix"对象指标向量组成员对于其行。
用法----------Usage----------
test.allele.switch(snps, snps2 = NULL, split = NULL, prior.df = 1)
参数----------Arguments----------
参数：snps
An object of class "SnpMatrix" or "XSnpMatrix"
一个对象类"SnpMatrix"或"XSnpMatrix"
参数：snps2
A second object of the same class as snps
一个的snps的同一类的第二个对象
参数：split
If only one SnpMatrix object supplied, a vector with the same number of elements as rows of snps. It must be capable of coercion to a factor with two levels.
如果只有一个SnpMatrix对象提供，与相同数目的元素snps行向量。它必须是能够强制的因素有两个层次。
参数：prior.df
A degree of freedom parameter for the prior distribution of the allele frequency prior.df (see Details)
一个程度的自由参数先验分布的等位基因频率prior.df（见详情）
Details
详情----------Details----------
This function calculates a Bayes factor for the comparison of the hypothesis that the alleles have been switched with the hypothesis that they have not been switched. This requires integration over the posterior distribution of the allele frequency. The prior is taken as a beta distribution with both parameters equal to prior.dfso that the prior is symmetric about 0.5. The default, prior.df=1 represents a uniform prior on (0,1).
此函数计算贝叶斯因子的假说比较等位基因已与假说，他们没有被切换开关。这就要求整合后的等位基因频率分布在。之前是作为测试等于prior.df的两个参数分布所以，之前是0.5左右对称。默认情况下，prior.df=1之前（0,1）的制服。
值----------Value----------
A vector containing the log (base 10) of the Bayes Factors for an allele switch.
含有一个基因开关的贝叶斯因子的log（基数为10）的一个向量。
作者（S）----------Author(s)----------
David Clayton <a href="mailto:david.clayton@cimr.cam.ac.uk">david.clayton@cimr.cam.ac.uk</a>
参见----------See Also----------
SnpMatrix-class, XSnpMatrix-class
SnpMatrix-class，XSnpMatrix-class
举例----------Examples----------
data(testdata)
#[]
# Call with two SnpMatrix arguments[调用两个SnpMatrix参数的]
#[]
cc <- as.numeric(subject.data$cc)
lbf1 <- test.allele.switch(Autosomes[cc==1,], Autosomes[cc==2,])
#[]
# Single matrix call (giving the same result)[单矩阵调用（提供相同的结果）]
#[]
lbf2 <- test.allele.switch(Autosomes, split=cc)
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注：
注1：为了方便大家学习，本文档为生物统计家园网机器人LoveR翻译而成，仅供个人R语言学习参考使用，生物统计家园保留版权。
注2：由于是机器人自动翻译，难免有不准确之处，使用时仔细对照中、英文内容进行反复理解，可以帮助R语言的学习。
注3：如遇到不准确之处，请在本贴的后面进行回帖，我们会逐渐进行修订。
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发表于 2012-2-26 14:49:14
