findDelta(siggenes)
findDelta()所属R语言包:siggenes
Finding the Threshold Delta
寻找阈值Delta
译者:生物统计家园网 机器人LoveR
描述----------Description----------
Computes the value of the threshold Delta for a given FDR or number of genes/variables in a SAM or EBAM analysis.
计算阈值Delta的一个给定的FDR或在SAM或EBAM分析基因/变量的值。
用法----------Usage----------
findDelta(object, fdr = NULL, genes = NULL, prec = 6, initial = NULL,
verbose = FALSE)
参数----------Arguments----------
参数:object
either a SAM or an EBAM object.
无论是SAM或EBAM对象。
参数:fdr
numeric value between 0 and 1 for which the threshold Delta and thus the number of genes/variables should be obtained. Only one of fdr and genes can be specified.
应获得的阈值Delta和基因/变量的0和1之间的数值。 fdr和genes可以指定只有一个。
参数:genes
integer specifying the number of genes/variables for which the threshold Delta and thus the estimated FDR should be obtained. Only one of fdr and genes can be specified.
整数,指定的基因/变量的数量应获得的阈值Delta,因此估计FDR。 fdr和genes可以指定只有一个。
参数:prec
integer indicating the precision of the considered Delta values.
整数,表示认为Delta值的精度。
参数:initial
a numeric vector of length two containing the minimum and the maximum value of Delta that is initially used in the search for Delta. Both values must be larger than 0. If object is an EBAM object, both values must also be smaller than or equal to 1. If not specified, the minimum is set to 0.1, and the maximum to either the maximum posterior (EBAM) or the maximum absolute distance between the observed and the corresponding expected values of the test statistic (SAM).
的长度含有最低和Delta的最大价值,最初是在Delta搜索使用两个数字向量。这两个值必须大于0。如果object是EBAM的对象,这两个值也必须小于或等于1。如果没有指定,最低为0.1,最大的,无论是最大后验(EBAM)或绝对的观察和测试统计(SAM)的相应预期值之间的最大距离。
参数:verbose
should more information about the search process be shown?
应该对搜索过程的详细信息显示?
值----------Value----------
If a value of Delta is found for the exact value of fdr or genes, then a vector of length 3 consisting of Delta and the corresponding number of genes and the estimated FDR. If such a value is not found, then a matrix with two rows and three columns, where the two rows contain the number of genes/variables and the estimated FDR for the two considered values of Delta that provide the closest upper and lower bounds to the desired FDR (if fdr is specified) or number of genes/variables (if genes is specified.)
如果一个Delta的价值被发现的精确值fdr或genes,然后一个长度为3的向量组成的Delta和相应的基因数量和估计FDR。如果没有找到这样一个值,然后有两行三列,两行包含两个Delta值提供最接近的上限和下限的基因/变量的数量和估计FDR的矩阵所需的FDR(fdr如果指定)或基因/变量的数量(如果genes指定。)
作者(S)----------Author(s)----------
Holger Schwender, <a href="mailto:holger.schwender@udo.edu">holger.schwender@udo.edu</a>
参见----------See Also----------
sam, ebam
sam,ebam
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注:
注1:为了方便大家学习,本文档为生物统计家园网机器人LoveR翻译而成,仅供个人R语言学习参考使用,生物统计家园保留版权。
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