norm1d(nudge)
norm1d()所属R语言包：nudge
Function for normalizing the mean and variance of average-across-replicates log ratios
功能标准化平均全面复制log比率的均值和方差
译者：生物统计家园网 机器人LoveR
描述----------Description----------
This performs a robust normalization of the variance of the (mean normalized) average-across-replicates log ratios by scaling the (mean normalized) average-across-replicates log ratio for each gene either by the standard deviation of the log ratios for that gene across replicates (if bigger than its absolute (mean normalized) average-across-replicates log ratio) or scaling by a constant (a quantile of the distribution of standard deviations of log ratios across replicates for all genes whose standard deviation was bigger than their absolute (mean normalized) average-across-replicates log ratio.
执行稳健的方差标准化（平均归一化）平均全面按比例复制log比率（平均归）平均横跨每一个基因的复制log的比例，由该基因的log比率的标准差整个复制（如果大于其绝对值（平均归一化）平均全面复制log比率）由一个常数或缩放（所有基因的复制log比整个标准偏差的分布的分位数的标准差是大于他们的绝对（平均归一）平均全面复制log比率。
用法----------Usage----------
norm1d(logratio, logintensity, span = 0.6, quant = 0.99, dye.swap = FALSE)
参数----------Arguments----------
参数：logratio
A multiple-column matrix of replicates of log (base 2) ratios of gene expressions in two samples.
一个多列的矩阵复制log（基数为2）两个样本中的基因表达的比率。
参数：logintensity
A multiple-column matrix of replicates of log (base 2) total intensities (defined as the product) of gene expressions in two samples.
一个多列的矩阵复制log（碱基）总强度在两个样本中的基因表达（定义为产品）。
参数：span
Proportion of data used to fit the loess regression of the average-across-replicates log ratios on the average-across-replicates log total intensities.
适合局部加权回归用于数据的比例平均全面复制log比对的平均跨重复记录的总强度。
参数：quant
Quantile to be used from the distribution of standard deviations of log ratios across replicates for all genes whose standard deviation was smaller than their absolute (mean normalized) average-across-replicates log ratio.
位数将用于从分布的标准偏差的log比跨所有的基因，其标准差小于其绝对复制（平均归一化）平均全面复制log的比例。
参数：dye.swap
A logical value indicating whether or not the data consists of a balanced dye swap (if FALSE a mean normalization will be performed prior to the variance normalization rather than a simple averaging across replicates).
一个逻辑值，该值指示数据是否包含一个平衡的染料互换（如果为FALSE平均标准化之前将进行整个复制，而不是一个简单的平均方差标准化）。
Details
详情----------Details----------
A balanced dye swap is a data set were the data are split into two sets of replicates (same number of replicates in each set) where one set has the reverse dye assignment of the other set.
一个平衡的染料交换是一个数据集的数据分割成两套（每套相同数量的复制）的复制一套有相反的另一套染料分配。
值----------Value----------
A vector of mean and variance normalized average-across-replicates log ratios.
一个向量的均值和方差归一化平均跨复制log率。
作者（S）----------Author(s)----------
N. Dean and A. E. Raftery
参考文献----------References----------
参见----------See Also----------
norm1c,norm1a,norm1b,norm2c,norm2d
norm1c，norm1a，norm1b，norm2c，norm2d
举例----------Examples----------
data(hiv)
lR<-log(hiv[,1:4],2)-log(hiv[,5:8],2)
lI<-log(hiv[,1:4],2)+log(hiv[,5:8],2)
lRnorm<-norm1d(lR,lI,dye.swap=TRUE)
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注：
注1：为了方便大家学习，本文档为生物统计家园网机器人LoveR翻译而成，仅供个人R语言学习参考使用，生物统计家园保留版权。
注2：由于是机器人自动翻译，难免有不准确之处，使用时仔细对照中、英文内容进行反复理解，可以帮助R语言的学习。
注3：如遇到不准确之处，请在本贴的后面进行回帖，我们会逐渐进行修订。
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发表于 2012-2-26 07:56:59
