nem.consensus(nem)
nem.consensus()所属R语言包:nem
Statistically stabile nested effects models
斯塔比尔的统计学模型嵌套影响
译者:生物统计家园网 机器人LoveR
描述----------Description----------
Performs bootstrapping (resampling with replacement) on E-genes and jackknife on S-genes to assess the statistical stability of networks. Only edges appearing with a higher frequency than a predescribed threshold in both procedures are regarded as statistical stable and appear in the so-called consensus network.
执行引导(更换重新取样)在E基因和评估网络的统计稳定的S-基因折刀。只出现在更高的频率比在这两个程序predescribed阈值的边缘被视为统计上的稳定,出现在所谓的共识网络。
用法----------Usage----------
nem.consensus(D,thresh=0.5, nboot=1000,inference="nem.greedy",models=NULL,control=set.default.parameters(unique(colnames(D))), verbose=TRUE)
## S3 method for class 'nem.consensus'
print(x, ...)
参数----------Arguments----------
参数:D
data matrix with experiments in the columns (binary or continous)
矩阵中列的实验数据(二进制或连续)
参数:thresh
only edges appearing with a higher frequency than "thresh" in both, bootstrap and jackknife procedure, are regarded as statistically stable and trust worthy
只有边缘比“阈值”的同时,引导和刀切过程中出现频率较高,被视为统计学稳定和值得信任
参数:nboot
number of bootstrap samples desired
引导所需的样品数
参数:inference
search to use exhaustive enumeration, triples for triple-based inference, pairwise for the pairwise heuristic, ModuleNetwork for the module based inference, nem.greedy for greedy hillclimbing, nem.greedyMAP for alternating MAP optimization using log odds or log p-value densities
search使用详尽列举,triples三重基于推理,pairwise为成对启发式,ModuleNetwork的模块为基础的推理,nem.greedy贪婪hillclimbing ,nem.greedyMAPp值交替图优化log赔率或log密度
参数:models
a list of adjacency matrices for model search. If NULL, an exhaustive enumeration of all possible models is performed.
邻接矩阵模型搜索列表。如果为NULL,详尽列举所有可能的模式进行。
参数:control
list of parameters: see set.default.parameters
参数列表:看到set.default.parameters
参数:verbose
do you want to see progression statements? Default: TRUE
你想看到进展的报表?默认:true
参数:x
nem object
NEM对象
参数:...
other arguments to pass
其他参数传递
Details
详情----------Details----------
Calls nem or nemModelSelection internally, depending on whether or not lambda is a vector and Pm != NULL.
调用nem或nemModelSelection内部,取决于与否的lambda是一个向量和下午!= NULL的。
值----------Value----------
consensus network (nem object)
共识网(NEM对象)
作者(S)----------Author(s)----------
Holger Froehlich
参见----------See Also----------
nem.bootstrap, nem.jackknife, nem.calcSignificance, nem
nem.bootstrap,nem.jackknife,nem.calcSignificance,nem
举例----------Examples----------
## Not run: [#无法运行:]
data("BoutrosRNAi2002")
D <- BoutrosRNAiDiscrete[,9:16]
nem.consensus(D, control=set.default.parameters(unique(colnames(D)), para=c(0.13,0.05)))
## End(Not run)[#结束(不运行)]
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注:
注1:为了方便大家学习,本文档为生物统计家园网机器人LoveR翻译而成,仅供个人R语言学习参考使用,生物统计家园保留版权。
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