MmPalateMiRNA-package(MmPalateMiRNA)
MmPalateMiRNA-package()所属R语言包：MmPalateMiRNA
R package compendium for the analysis of murine palate two-color miRNA expression data
R为小鼠腭裂两色的miRNA表达数据分析软件包汇编
译者：生物统计家园网 机器人LoveR
描述----------Description----------
R package compendium for the analysis of two-color miRNA expression data, during the period of murine embryonic palate development (gestational days (GD) 12, 13, and 14). Samples were hybridized to Miltenyi Biotech miRXplore Microarrays. The compendium covers a wide range of steps which occur in a typical miRNA microarray data analysis, including pre-processing, normalization, differential expression analysis, clustering, target identification, and gene-set enrichment analysis.
R为两色的miRNA表达数据分析软件包汇编，在小鼠胚胎腭发展时期（妊娠天（广东），12，13，14）。样品进行杂交，美天旎生物技术miRXplore微阵列。 “汇编”涵盖了范围广泛发生在一个典型的miRNA微阵列数据分析，包括前处理，规范化，差异表达分析，聚类分析，目标识别，基因组富集分析的步骤。
Details
详情----------Details----------
The package contains several functions which are helpful during the pre-processing steps of array data, which are specific to RGList objects and, in the case of the fixOutliers and fixMVs functions, depend on the replicated structure of Miltenyi Biotech miRXplore Microarrays. Additionally, methods are available to produce diagnostic plots for RGList objects and lists of normalized data sets (MAList and / or NChannelSet objects), which build on the generic functions in lattice. Lastly, the main focus of the package is the package vignette "MmPalateMiRNA", which contains an extended example covering the typical steps in an miRNA microarray data analysis.
包中包含多种功能，这有助于在阵列中的数据，具体RGList对象的在fixOutliers和fixMVs功能的情况下，前处理步骤，取决于天旎生物技术miRXplore微阵列的复制结构。此外，方法是可用的生产RGList对象和规范化的数据集列表（MAList和/或NChannelSet对象）的诊断图，其中上lattice通用功能建设。最后，包的主要焦点是包小插曲“MmPalateMiRNA”，其中包含一个扩展的例子，覆盖在miRNA的芯片数据分析的典型步骤。
作者（S）----------Author(s)----------
Guy Brock, Partha Mukhopadhyay, Vasyl Pihur, Bob Green, M. Michele Pisano
Maintainer: Guy Brock <guy.brock@louisville.edu>
参考文献----------References----------
Developmental microRNA expression profiling of murine embryonic orofacial tissue. Birth Defects Res A Clin Mol Teratol, 88(7):511-34, 2010.
Reproducible research: a bioinformatics case study. Stat Appl Genet Mol Biol, 4:Article2, 2005.
C. Drescher, W. Huber, R. Gentleman, and M. Tewari. Quality assessment and data analysis for microRNA expression arrays. Nucleic Acids Res, 37(2):e17, 2009.
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注：
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发表于 2012-2-26 01:07:10
