Dataset of class MEDMEset for testing MEDME
测试MEDME数据集类MEDMEset
译者:生物统计家园网 机器人LoveR
描述----------Description----------
This dataset contains a subset of the data reported in references. It contains normalized un-smoothed probe-level MeDIP enrichment for almost 50000 probes. This is a random subset of a custom Nimblegen chromosome X tiling array. It is a two channels array with an resolution of 100bp and oligos of 60nt. The M value is reported only. The fullyMet column of the logR slot contains data from a calibration experiments where MeDIP has been applied to a fully methylated sample. The last two columns NBMEL and YUSAC2 contain DNA-methylation experimental data for two cell strains: NBMEL are newborn normal melanocytes cells and YUSAC2 a melanoma strain. Data was processed with within and between array normalization. The full dataset contains almost 380K probes. See references for details. Chromosome, genomic position and logR of probes can be accessed with the methods chr, pos and logR respectively.
该数据集包含在文献报道的数据的一个子集。它包含归联合国近50000探针平滑探针水平MeDIP富集。这是一个定制的NimbleGen X染色体平铺阵列的随机子集。这是两个通道阵列与100个基点和60nt的寡核苷酸的决议。据悉M值。的logR插槽fullyMet列包含从校准MeDIP已被应用到一个完全甲基化的样本的实验数据。最后两列NBMEL和YUSAC2包含两个单元株的DNA甲基化的实验数据:NBMEL是新生儿正常的黑色素单元和YUSAC2黑色素瘤株。数据处理与内部及相互之间的数组标准化。完整的数据集包含几乎380K探针。有关详情,请参阅参考。分别与方法CHR,POS logR的的染色体,基因组的位置和探针logR可以访问。
Please note that the original genomic coordinates were mapped to the hg17 human genome. These have been converted to hg18 using the LiftOver USCS tool available online for batch conversion.
请注意,被映射到hg17人类基因组的原始基因组坐标。这些已转为hg18 LiftOver USCS工具可在网上使用批量转换。