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R语言 GSEAlm包 resplot()函数中文帮助文档(中英文对照)

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发表于 2012-2-25 21:18:31 | 显示全部楼层 |阅读模式
resplot(GSEAlm)
resplot()所属R语言包:GSEAlm

                                         Simple Graphical Summaries for Gene Set Enrichment Analysis
                                         基因组富集分析简单的图形摘要

                                         译者:生物统计家园网 机器人LoveR

描述----------Description----------

Diagnostic plots for GSEA. 'resplot' and 'restrip' group residuals (or expression levels) from a specific gene-set by sample. 'mnDiffPlot' shows mean expression differences for a dichotomous phenotype, by gene, for a specific gene set.
GSEA诊断图。 “resplot”和“restrip组残差从特定的基因组由样品(或表达水平)。 “mnDiffPlot”节目,平均为二元型基因的表达差异,对于一个特定的基因组。


用法----------Usage----------


resplot(GSname = "All", resmat, incidence = dumminc(resmat), fac,
     atomic = "Gene", core.text = "Residuals by Sample",
     yname = "Standardized Residual", xname = "Sample ID",
     ID = colnames(resmat), lims = 0, gnames = levels(factor(fac)),
     prefix = "", horiz = FALSE, colour=5,pch='+',...)

restrip(GSname = "All", resmat, incidence = dumminc(resmat), fac,
   atomic = "Gene", core.text = "Residuals by Sample",
  yname = "Standardized Residual", xname = "Sample ID", ID = colnames(resmat),
  gnames = levels(factor(fac)), prefix = "", colour=c(2:4,6), resort=TRUE,
  horiz = FALSE, resort.fun=num.positive, pch='+', ...)

mnDiffPlot(GSname = "All", exprmat, incidence = dumminc(exprmat), fac,
  atomic = "Gene", core.text = paste("Mean Expression Difference by",atomic),
  yname="Log Expression Ratio", xname="Log Expression",
  gnames = levels(factor(fac)), prefix = "", fitline=FALSE, varsize=FALSE,



参数----------Arguments----------

参数:GSname
Gene-set Name. See "Details".
基因组的名称。查看“详细信息”。


参数:resmat,exprmat
Numerical matrix with the values to be plotted. See "Details".  
值的数值矩阵绘制。查看“详细信息”。


参数:incidence
Gene-set 0/1 membership matrix  
基因组0/1隶属度矩阵


参数:fac
The phenotypical variable to plot by. Must be discrete. For 'mnDiffPlot', must be dichotomous.
绘制的表型变量。必须是独立的。为mnDiffPlot,必须是二分法。


参数:atomic
string identifying the meaning of rows in the data matrix. Defaults to "Gene".  
字符串识别数据矩阵中的行的意义。默认为“基因”。


参数:core.text,gnames,prefix,xname,yname
strings controlling the text of main and axis captions  
控制的主要和轴标题的文本字符串


参数:ID
Group names associated with the data matrix columns  
组相关数据矩阵的列名


参数:lims
plotting limits for the response axis
为响应轴绘制的限制


参数:horiz
logical: whether the boxplots or strips should be horizontal (defaults to FALSE)
逻辑:盒形或条状是否应该水平(默认为false)


参数:colour
color of boxplot filling ('resplot') or symbols ('restrip')
颜色填充盒形图(resplot)或符号(restrip)


参数:pch
the plotting symbol
图形符号


参数:resort
('restrip' only) whether to sort groups for better visibility
(restrip只)有否更好的可视性组排序


参数:resort.fun
('restrip' only) what function to sort groups by. Ignored unless 'resort==TRUE'. See stripchart documentation for more details
(“restrip只)函数进行排序分组。被忽略,除非“度假== TRUE”。详情请参阅stripchart文件


参数:fitline
('mnDiffPlot' only) logical: whether a loess fit should be plotted
(“mnDiffPlot唯一的)逻辑:是否的FIT应绘制黄土


参数:varsize
('mnDiffPlot' only) logical: whether symbol sizes should be proportional to (t-test style) standard errors
(“mnDiffPlot)逻辑:符号大小是否应该成正比(t检验作风)标准误差


参数:reverse
('mnDiffPlot' only)logical: whether the factor's order should be reversed so that the second level is on the x-axis rather than the first one
(“mnDiffPlot)逻辑:使第二个层次是在x轴,而不是第一个因素的订单是否应扭转


参数:...
Additional graphical parameters passed on to the generic plotting functions.
额外的图形参数传递到通用的绘图功能。


Details

详情----------Details----------

These functions provide simple graphical summaries for processed gene-expression data, or other similar datasets for which matrix form is useful. They are tailored predominantly for GSEA, but are useful in general as well.
这些功能提供简单的图形摘要基因表达数据处理,或其他类似的数据集,是有用的矩阵形式。他们主要为GSEA量身定做,但一般也非常有用。

'resplot' calls boxplot and 'restrip' calls stripchart; both summarize *all* data points from those rows in 'resmat' which are members in the gene-set specified by 'GSname'. The summary is by column. For each level of 'fac' there will be a separate pane.
“resplot调用boxplot”restrip的来电stripchart;既总结所有数据点从在“resmat那些行,这是在基因组由”GSname指定成员。摘要列。对于每个因素的水平会有一个单独的窗格中。

'mnDiffPlot' calls plot; it plots the mean differences, by row, between columns belonging to the two groups specified by 'fac', as a function of the mean values for the first group alone. Each row translates to a single point on the graph. Again, the summary is only for rows indicated by 'GSname'.
“mnDiffPlot”呼叫plot;图的平均差异,按行,列属于“FAC”指定的两个组之间的功能仅在第一组的平均值。每一行转换为单点上的图形。再次,总结是只为GSname表示行。

For gene-set selective plots to properly work, the incidence matrix needs to have non-empty row names, and 'GSname' must match one of them.
关联矩阵为基因组选择性图的正常工作,需要有非空行名称,必须符合“GSname其中之一。

If both 'GSname' and 'incidence' are left blank, automatic utilities are called which help generate a summary of the entire matrix, by column.
如果都“GSname”和“发病率”都留空,被称为自动公用事业有助于产生整个矩阵的总结,由列。

All functions plot a reference line signalling zero. 'mnDiffPlot' also optionally plots a loess fit for expression differences (if 'fitline=TRUE').
所有的功能,绘制参考线,信号为零。 “mnDiffPlot也可选择图为差异表达的黄土适合(如果fitline = TRUE”)。


注意----------Note----------

One can use 'resplot'/'restrip' to plot raw expression values rather than residuals; it all depends on what's in the data matrix.
一个可以使用“resplot/restrip绘制原始表达式的值,而不是残差,这一切取决于对数据矩阵是什么。


作者(S)----------Author(s)----------


Assaf Oron



参见----------See Also----------

boxplot,plot,stripchart,par,GOmnplot
boxplot,plot,stripchart,par,GOmnplot


举例----------Examples----------



data(sample.ExpressionSet)
lm1 = lmPerGene(sample.ExpressionSet,~sex)
r1 = getResidPerGene(lm1)
### now a boxplot of all residuals by sample[##现在所有残差由样品的盒形图]
resplot(resmat=exprs(r1),fac=sample.ExpressionSet$sex)
### This plot is not very informative because of some gross outliers;[##这个图是不会因为一些毛离群非常翔实;]
### try this instead[#尝试这种替代]
resplot(resmat=exprs(r1),fac=sample.ExpressionSet$sex,lims=c(-5,5))

### stripchart for first 10 genes[#第10个基因stripchart]
restrip(resmat=exprs(r1)[1:10,],fac=sample.ExpressionSet$type,prefix="Not")

### note the wild trajectory of the loess fit:[#注意的黄土适合野生轨迹:]
mnDiffPlot(exprmat=exprs(sample.ExpressionSet),fac=sample.ExpressionSet$type,xname="Raw Expression",yname="Expression Difference",fitline=TRUE)

转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。


注:
注1:为了方便大家学习,本文档为生物统计家园网机器人LoveR翻译而成,仅供个人R语言学习参考使用,生物统计家园保留版权。
注2:由于是机器人自动翻译,难免有不准确之处,使用时仔细对照中、英文内容进行反复理解,可以帮助R语言的学习。
注3:如遇到不准确之处,请在本贴的后面进行回帖,我们会逐渐进行修订。
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