transScores(GGtools)
transScores()所属R语言包:GGtools
obtain the top trans associations for each SNP in an smlSet
每个SNP反协会在smlSet获得
译者:生物统计家园网 机器人LoveR
描述----------Description----------
obtain the top trans associations for each SNP in an smlSet
每个SNP反协会在smlSet获得
用法----------Usage----------
transScores(smpack, snpchr = "chr1", rhs, K = 20, targdirpref = "tsco", geneApply = lapply,
chrnames = paste("chr", as.character(1:22), sep = ""), geneRanges = NULL, snpRanges = NULL,
radius = 2e+06, renameChrs = NULL, probesToKeep = NULL, batchsize = 200, genegran = 50, shortfac = 10, wrapperEndo = NULL)
mtransScores (smpackvec, snpchr = "chr1", rhslist, K = 20, targdirpref = "multtsco",
geneApply = lapply, chrnames = paste("chr", as.character(1:22), sep=""),
geneRanges = NULL, snpRanges = NULL, radius = 2e+06, renameChrs=NULL,
batchsize=200, genegran=50, probesToKeep=NULL, shortfac=10, wrapperEndo=NULL)
参数----------Arguments----------
参数:smpack
name of package holding eset.rda providing 'ex' ExpressionSet when loaded, and holding SnpMatrix instances in inst/parts
包控股eset.rda提供“前”ExpressionSet加载时,INST /零件SnpMatrix实例名称
参数:smpackvec
vector of names of package holding eset.rda providing 'ex' ExpressionSet when loaded, and holding SnpMatrix instances in inst/parts
向量控股eset.rda包名称为“前”ExpressionSet加载时,INST /零件SnpMatrix实例的
参数:snpchr
name or vector of chromosome names of SNPs of interest
向量的染色体利益的SNPs名称或名称
参数:rhs
right hand side of snp.rhs.tests model for which expression is left hand side, e.g., covariates other than genotype
模型的表达snp.rhs.tests右侧左侧,例如,协变量比基因型
参数:rhslist
list of right hand side of snp.rhs.tests model for which expression is left hand side, e.g., covariates other than genotype, one per element of smpackvec
模型的表达snp.rhs.tests右侧的列表左侧,例如,协变量其他超过基因型,每一个元素smpackvec
参数:K
number of most highly associated features to be retained
要保留功能最高度相关的数
参数:targdirpref
prefix of target folder name (passed to eqtlTests
前缀的目标文件夹的名称(传递eqtlTests的
参数:geneApply
passed to eqtlTests
传递eqtlTests的
参数:chrnames
names of chromosomes harboring genes that will be tested for association with genotype
窝藏将用于测试与基因型的基因染色体的名字
参数:geneRanges
list of GRanges-class instances containing chromosomal coordinate defined regions occupied by genes, with regions partitioned by chromosomes, and list element names as given in chrnames above
GRanges-class以上chrnames包含由染色体由基因染色体协调定义占领的区域,划分区域的实例,列表中的元素名称列表
参数:snpRanges
list of GRanges-class instances with SNP addresses
GRanges-class实例与SNP地址列表
参数:radius
radius within which an association is considered cis and therefore the corresponding test statistic is set to zero
半径内,协会被认为是独联体,因此,相应的检验统计量设置为零
参数:renameChrs
passed to getSS
传递getSS的
参数:probesToKeep
passed to getSS
传递getSS的
参数:batchsize
defines batch size for ffrowapply
定义为ffrowapply批量大小
参数:genegran
passed to eqtlTests
传递eqtlTests的
参数:shortfac
passed to eqtlTests
传递eqtlTests的
参数:wrapperEndo
a function accepting and returning an smlSet instance
一个函数接受和返回smlSet实例
值----------Value----------
a list with elements
一个元素的列表
参数:scores
an S by K ff matrix where S is number of SNPs, K is number of best features to be retained, with element s,k the kth largest score statistic among association tests computed for SNP s
杀敌矩阵S是单核苷酸多态性的数量,S,K是最好要保留功能,元素S,k为第k个最大之间关联的SNP小号计算测试得分统计
参数:inds
an S by K ff matrix with s,k element telling which element of guniv (see below) is the gene giving the kth largest score statistic for association
杀敌矩阵,S,K元素,告诉元素guniv(见下文)的基因,使第k个最大的协会得分统计小号
参数:guniv
the vector of gene identifiers defining the universe of genes tested
基因标识的向量,基因测试确定宇宙
参数:snpnames
vector of SNP identifiers
向量的SNP标识符
参数:call
the call used to create the result
用于创建结果的呼叫
作者(S)----------Author(s)----------
VJ Carey <stvjc@channing.harvard.edu>
举例----------Examples----------
## Not run: [#无法运行:]
library(GGdata)
# need to define the geneRanges and snpRanges ...[需要定义的geneRanges和snpRanges ...]
transScores("GGdata", "20", renameChrs="chr20", chrnames="chr21")
## End(Not run)[#结束(不运行)]
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注:
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