dyebias-package(dyebias)
dyebias-package()所属R语言包:dyebias
The GASSCO method for correcting for slide-dependent gene-specific dye bias
GASSCO幻灯片依赖特定基因的染料偏见纠正方法
译者:生物统计家园网 机器人LoveR
描述----------Description----------
Many two-colour hybridizations suffer from a dye bias that is both gene-specific and slide-specific. The former depends on the content of the nucleotide used for labeling; the latter depends on the labeling percentage. The slide-dependency was hitherto not recognized, and made addressing the artefact impossible. Given a reasonable number of dye-swapped pairs of hybridizations, or of same vs. same hybridizations, both the gene- and slide-biases can be estimated and corrected using the GASSCO method (Margaritis et al., Mol. Sys. Biol. 5:266 (2009), doi:10.1038/msb.2009.21)
许多两色的杂交遭受从染料的偏见,认为是特定基因和幻灯片。前者取决于标签用于核苷酸的内容;后者取决于标签的百分比。幻灯片依赖是迄今尚未确认,并提出解决的人工制品是不可能的。鉴于合理数量的杂交,或相同与相同的杂交对染料交换,无论是基因和幻灯片可以使用GASSCO方法(Margaritis等,为SYS。生物学估计和纠正偏见。 :266(2009),DOI:10.1038/msb.2009.21)
Details
详情----------Details----------
作者(S)----------Author(s)----------
Philip Lijnzaad and Thanasis Margaritis<br>
Philip Lijnzaad <p.lijnzaad@umcutrecht.nl> (Maintainer).
参见----------See Also----------
dyebias.application.subset, dyebias.apply.correction, dyebias.boxplot, dyebias.estimate.iGSDBs, dyebias.monotonicity, dyebias.monotonicityplot, dyebias.rgplot, dyebias.trendplot.
dyebias.application.subset,dyebias.apply.correction,dyebias.boxplot,dyebias.estimate.iGSDBs,dyebias.monotonicity,dyebias.monotonicityplot,dyebias.rgplot,dyebias.trendplot。
转载请注明:出自 生物统计家园网(http://www.biostatistic.net)。
注:
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